Perineuronal nets: subtle structures with large implications

H Carceller, Y Gramuntell, P Klimczak… - The …, 2023 - journals.sagepub.com
Perineuronal nets (PNNs) are specialized structures of the extracellular matrix that surround
the soma and proximal dendrites of certain neurons in the central nervous system …

Casting a wide net: role of perineuronal nets in neural plasticity

BA Sorg, S Berretta, JM Blacktop… - Journal of …, 2016 - Soc Neuroscience
Perineuronal nets (PNNs) are unique extracellular matrix structures that wrap around certain
neurons in the CNS during development and control plasticity in the adult CNS. They appear …

Differential expression and cell-type specificity of perineuronal nets in hippocampus, medial entorhinal cortex, and visual cortex examined in the rat and mouse

KK Lensjø, AC Christensen, S Tennøe, M Fyhn… - eneuro, 2017 - eneuro.org
Perineuronal nets (PNNs) are specialized extracellular matrix (ECM) structures that
condense around the soma and proximal dendrites of subpopulations of neurons. Emerging …

[HTML][HTML] An extracellular perspective on CNS maturation: perineuronal nets and the control of plasticity

D Carulli, J Verhaagen - International Journal of Molecular Sciences, 2021 - mdpi.com
During restricted time windows of postnatal life, called critical periods, neural circuits are
highly plastic and are shaped by environmental stimuli. In several mammalian brain areas …

The roles of perineuronal nets and the perinodal extracellular matrix in neuronal function

JW Fawcett, T Oohashi, T Pizzorusso - Nature Reviews Neuroscience, 2019 - nature.com
Perineuronal nets (PNNs) are extracellular matrix (ECM) chondroitin sulfate proteoglycan
(CSPG)-containing structures that surround the soma and dendrites of various mammalian …

Perineuronal nets protect long-term memory by limiting activity-dependent inhibition from parvalbumin interneurons

W Shi, X Wei, X Wang, S Du, W Liu… - Proceedings of the …, 2019 - National Acad Sciences
Perineuronal nets (PNNs), a complex of extracellular matrix molecules that mostly surround
GABAergic neurons in various brain regions, play a critical role in synaptic plasticity. The …

Deconstructing the perineuronal net: cellular contributions and molecular composition of the neuronal extracellular matrix

KA Giamanco, RT Matthews - Neuroscience, 2012 - Elsevier
Perineuronal nets (PNNs) are lattice-like substructures of the neural extracellular matrix that
enwrap particular populations of neurons throughout the central nervous system. Previous …

Proteolytic remodeling of perineuronal nets: effects on synaptic plasticity and neuronal population dynamics

P Lorenzo Bozzelli, S Alaiyed, E Kim, S Villapol… - Neural …, 2018 - Wiley Online Library
The perineuronal net (PNN) represents a lattice‐like structure that is prominently expressed
along the soma and proximal dendrites of parvalbumin‐(PV‐) positive interneurons in varied …

Perineuronal nets affect parvalbumin expression in gaba ergic neurons of the mouse hippocampus

J Yamada, T Ohgomori, S Jinno - European Journal of …, 2015 - Wiley Online Library
Recent studies have suggested that the perineuronal net (PNN), a specialised extracellular
matrix structure, and parvalbumin (PV), an EF‐hand calcium‐binding protein, are involved in …

[HTML][HTML] A sweet talk: the molecular systems of perineuronal nets in controlling neuronal communication

HM Van't Spijker, JCF Kwok - Frontiers in integrative neuroscience, 2017 - frontiersin.org
Perineuronal nets (PNNs) are mesh-like structures, composed of a hierarchical assembly of
extracellular matrix molecules in the central nervous system (CNS), ensheathing neurons …