Systemic sclerosis is an autoimmune inflammatory disorder of unknown etiology
characterized by pronounced fibroproliferative alterations in the microvasculature, and …

Fibrosis is a pathological process characterized by excessive accumulation of connective
tissue components in an organ or tissue. Fibrosis is produced by deregulated wound …

Systemic sclerosis (SSc), also referred to as systemic scleroderma or scleroderma, is a rare,
complex immune-mediated connective tissue disease characterized by progressive skin …

Systemic sclerosis (SSc) is an autoimmune disease characterized by significant vascular
alterations and multi-organ fibrosis. Microvascular alterations are the first event of SSc and …

Systemic sclerosis is a chronic autoimmune disease of still not fully understood
pathogenesis. Fibrosis, vascular wall damage, and disturbances of innate and acquired …

Systemic sclerosis (SSc) is a severe autoimmune disease that is characterized by vascular
abnormalities, immunological alterations and fibrosis of the skin and internal organs. The …

Systemic sclerosis (SS c) is a multisystem autoimmune disease characterized by
vasculopathy and tissue fibrosis of the skin and various internal organs. A series of genetic …

The pathogenesis of Systemic Sclerosis (SSc) is extremely complex, and despite extensive
studies, the exact mechanisms involved are not well understood. Numerous recent studies …

Systemic sclerosis (SSc) is a chronic autoimmune disease with a high morbidity and
mortality. Skin and organ fibrosis are key manifestations of SSc, for which no generally …

Systemic sclerosis (SSc) is characterized by extensive fibrosis, vasculopathy and activation
of the immune system. Fibrosis can be caused by profibrotic cytokines, such as transforming …