Los virus de influenza A (IAVs) son los responsables de brotes pandémicos y de la mayoría
de las epidemias anuales en los seres humanos, aves y cerdos. Los virus de influenza A se …

During lasts years, an increase in the number of outbreaks involving highly pathogenic
avian influenza viruses (HPAIV) has been reported in poultry and wild birds (Lupiani and …

Introduction: Influenza virus has several conserved peptides which have the capacity to be
used as suitable candidates for appropriate and stable vaccine production against different …

Influenza A viruses are a respiratory pathogen that cause annual epidemics as well as many
well-known pandemics such as Russian flu (1889), Spanish flu (1918), Asian Flu (1957) and …

Influenza A viruses are a major threat to human health and inflict a significant public health
challenge worldwide. Hemagglutinin (HA) is the main contributor to the infectivity of the virus …

Materials and Methods: In this study, recombinant HA2 protein comprising fusion peptide
was expressed in E. coli, purified using Ni-TED columns, refolded and desalted by dialysis …

Influenza infection occurs in as much as 5–15% of the world population, resulting in 3–5
million cases of severe illness and up to 500,000 deaths annually. According to the CDC, on …

The lack of universal influenza vaccine is a global health problem. The protective properties
of current influenza vaccines are limited as the globular head domain of hemagglutinin (HA) …

The influenza virus is able to continually evade the immune response through the rapid
mutation of the dominant epitopes on its surface, thus making periodic vaccinations a …

Last 100 years have witnessed two pandemic outbreaks of H1N1 influenza viz. Spanish flu
in 1918 and swine flu in 2009. It has been the most prevalent subtype of influenza virus in …