Within the past year the importance of heterogeneous nucleation in bone mineralization has
been revealed by studies from different fields of calcified tissue research. These new …

In this chapter, we describe the function and structure of bone as well as the interaction
between its main constituents with a specific focus on the mechanisms of bone …

Bone is a hierarchically structured composite material which, in addition to its obvious
biological value, has been well studied by the materials engineering community because of …

Most of the studies on biomineralization have focused on calcification and silicification, the
two systems that predominate in nature in the construction of skeletal or integumental hard …

Bone mineralization is a ubiquitous process among vertebrates that involves a dynamic
physical/chemical interplay between the organic and inorganic components of bone tissues …

In vivo mineralization is characterized by mineral and matrix disposal in proper orientation
and relationships. This chapter will give an overview of bone mineralization starting with the …

Mineralized extracellular matrix formation is representative for the osteoinductive capacity of
biomaterials and is often tested in vitro. Characteristics of in vitro mineralization of primary …

The development of bone is a complex process that involves cellular, extracellular, and
physicochemical events. Here, the overall process of bone formation is reviewed from a …

This manuscript considers certain aspects of mineral deposition in bone and other
vertebrate calcifying tissues in order to examine physical, chemical, and biological factors …

Background Bone regeneration research is currently ongoing in the scientific community.
Materials approved for clinical use, and applied to patients, have been developed and …