Corticosterone differentially regulates bax, bcl-2 and bcl-x mRNA levels in the rat hippocampus

SP Cardenas, C Parra, J Bravo, P Morales, HE Lara… - Neuroscience …, 2002 - Elsevier
It has previously been shown that adrenalectomy (ADX) produces apoptosis in the granule
cell of the dentate gyrus (DG), and that this effect is prevented by corticosterone …

Adrenalectomy regulates apoptotic-associated genes in rat hippocampus

M Greiner, S Cárdenas, C Parra, J Bravo, AM Avalos… - Endocrine, 2001 - Springer
Morphological studies of granular neurons of the hippocampus have shown that
adrenalectomy (ADX) induces the cell death of granular neurons, an effect prevented by …

Effects of long-term adrenalectomy on apoptosis and neuroprotection in the rat hippocampus

S Andrés, S Cárdenas, C Parra, J Bravo, M Greiner… - Endocrine, 2006 - Springer
Reduction in corticosterone by acute adrenalectomy (5 d) promotes apoptosis in dentate
gyrus (DG) granular neurons, an effect concomitant with variations in the expression of the …

[HTML][HTML] Adrenalectomy promotes a permanent decrease of plasma corticoid levels and a transient increase of apoptosis and the expression of Transforming Growth …

JA Bravo, CS Parra, S Arancibia, S Andrés, P Morales… - BMC neuroscience, 2006 - Springer
Background Corticosterone reduction produced by adrenalectomy (ADX) induces apoptosis
in dentate gyrus (DG) of the hippocampus, an effect related to an increase in the expression …

The in vivo time course for elimination of adrenalectomy-induced apoptotic profiles from the granule cell layer of the rat hippocampus

Z Hu, K Yuri, H Ozawa, H Lu… - Journal of Neuroscience, 1997 - Soc Neuroscience
Although apoptotic cellular degeneration has been reported to be extremely rapid with the
use of in vitro models, the time needed to clear apoptotic neurons in the in vivo brain is …

Dexamethasone induces dendritic alteration but not apoptosis in the neurons of the hippocampus in postnatal rats

CK Tan, J Yan, C Ananth, C Kaur - Neuroscience letters, 2002 - Elsevier
One day old rats received daily injections of dexamethasone and were sacrificed 24 h after
the 1st and 7th injections. Neuronal death by apoptosis in the hippocampus was …

Gene expression changes in single dentate granule neurons after adrenalectomy of rats

Y Qin, S Nair, H Karst, E Vreugdenhil, N Datson… - Molecular brain …, 2003 - Elsevier
Removal of corticosterone by adrenalectomy induces apoptosis 3 days later, in some, but
not all, rat dentate granule cells. We hypothesized that individual dentate cells trigger …

Dexamethasone does not prevent seven-day ADX-induced apoptosis in the dentate gyrus of the rat hippocampus

CD Hornsby, J Grootendorst, E Ronald de Kloet - Stress, 1996 - Taylor & Francis
Long-term adrenalectomy (ADX) is known to result in apoptosis within the dentate gyrus of
the rat hippocampus. While the underlying mechanism is still unclear, adrenal steroids …

Time-course of hippocampal granule cell degeneration and changes in adult neurogenesis after adrenalectomy in rats

SC Spanswick, JR Epp, RJ Sutherland - Neuroscience, 2011 - Elsevier
The hippocampus maintains the remarkable ability to generate new neurons throughout the
lifespan. Progenitor cells in the subgranular zone give rise mainly to granule cells that …

Ultrastructural analysis of the hippocampus of adult rats after long-term adrenalectomy

A Islam, J Westman, N Bogdanovic, IA Suliman… - Brain research, 1999 - Elsevier
Removal of adrenal steroids modulates various functions in the brain. However,
adrenalectomy (ADX) induced cell death in the hippocampal formation of the adult rat is a …