Negative impact of DEP exposure on human airway epithelial cell adhesion, stiffness, and repair

B Doornaert, V Leblond, S Galiacy… - … of Physiology-Lung …, 2003 - journals.physiology.org
Epidemiological and experimental studies suggest that diesel exhaust particles (DEPs) may
be associated with increased respiratory mortality and morbidity. Several recent studies …

Human bronchial epithelial cells exposed in vitro to diesel exhaust particles exhibit alterations in cell rheology and cytotoxicity associated with decrease in antioxidant …

R Seriani, CEC de Souza, PG Krempel… - … Science and Pollution …, 2016 - Springer
Diesel exhaust particles (DEPs) from diesel engines produce adverse alterations in cells of
the airways by activating intracellular signaling pathways and apoptotic gene …

[HTML][HTML] Multi-cellular human bronchial models exposed to diesel exhaust particles: assessment of inflammation, oxidative stress and macrophage polarization

J Ji, S Upadhyay, X Xiong, M Malmlöf… - Particle and fibre …, 2018 - Springer
Background Diesel exhaust particles (DEP) are a major component of outdoor air pollution.
DEP mediated pulmonary effects are plausibly linked to inflammatory and oxidative stress …

Toxicity effects of short term diesel exhaust particles exposure to human small airway epithelial cells (SAECs) and human lung carcinoma epithelial cells (A549)

M Tang, Q Li, L Xiao, Y Li, JL Jensen, TG Liou, A Zhou - Toxicology letters, 2012 - Elsevier
In this study, confocal Raman spectroscopy, atomic force microscope (AFM) and multiplex
ELISA were applied to analyze the biophysical responses (biomechanics and …

Benzene-extracted components are important for the major activity of diesel exhaust particles: effect on interleukin-8 gene expression in human bronchial epithelial …

S Kawasaki, H Takizawa, K Takami… - American journal of …, 2001 - atsjournals.org
Epidemiologic and experimental studies suggest that diesel exhaust particles (DEPs) may
be related to increasing respiratory mortality and morbidity. We have shown that DEPs …

Long term exposure to environmental concentrations of diesel exhaust particles does not impact the phenotype of human bronchial epithelial cells

CC Savary, N Bellamri, C Morzadec, S Langouët… - Toxicology in Vitro, 2018 - Elsevier
Chronic exposure to diesel engine exhausts is associated with an increased risk of
pulmonary diseases including lung cancer. Diesel engine exhausts contain large amounts …

The Effect of Diesel Exhaust Particles on Cell Function and Release of Inflammatory Mediators from Human Bronchial Epithelial Cells In Vitro

H Bayram, JL Devalia, RJ Sapsford… - American journal of …, 1998 - atsjournals.org
Animal studies have reported that diesel exhaust particles (DEP), which constitute an
important fraction of particulate air pollution, lead to inflammation and/or damage of the …

Pulmonary exposure to diesel exhaust particles enhances coagulatory disturbance with endothelial damage and systemic inflammation related to lung inflammation

K Inoue, H Takano, M Sakurai, T Oda… - Experimental …, 2006 - journals.sagepub.com
Pulmonary exposure to diesel exhaust particles (DEP) enhances lung inflammation related
to bacterial endotoxin (lipopolysaccharide [LPS]) in mice. Severe lung inflammation can …

[HTML][HTML] Effects of diesel exhaust particles on human lung epithelial cells: an in vitro study

G Mazzarella, F Ferraraccio, MV Prati, S Annunziata… - Respiratory …, 2007 - Elsevier
Atmospheric particulate matter (PM), an ingredient of urban pollution matter, is a mixture of
solid and liquid particles differing in origin, dimension and composition. There is big concern …

[HTML][HTML] Diesel exhaust particles increase IL-1β-induced human β-defensin expression via NF-κB-mediated pathway in human lung epithelial cells

HY Nam, EK Ahn, HJ Kim, Y Lim, CB Lee… - Particle and fibre …, 2006 - Springer
Background Human β-defensin (hBD)-2, antimicrobial peptide primarily induced in epithelial
cells, is a key factor in the innate immune response of the respiratory tract. Several studies …