Model lipid membranes have long been employed in a variety of biophysical techniques to
circumvent the complexity of natural membranes when studying their constituents or …

Abstract Solid-state Nuclear Magnetic Resonance (NMR) in combination with magnetically
aligned discoidal lipid mimics allows for studying the conformations of membrane proteins in …

Phospholipid bicelles are valuable membrane model systems to study membrane proteins
by NMR and other physicochemical techniques. The range of bicelle compositions that are …

We have created a stable bicelle system capable of forming micrometer-scale lipid domains
that orient in a magnetic field, suitable for structural biology determination in solid-state …

In this thesis novel NMR techniques for the study of phospholipid bilayers and bilayer-bound
peptides in magnetically oriented media (bicelles) are presented. Bicelles are model …

It is challenging to find membrane mimics that stabilize the native structures, dynamics, and
functions of membrane proteins. In a recent advance, nanodiscs have been shown to …

We present a new membrane mimetic system using a membrane softening detergent
commonly known as Tween 80 (TW80), to form oriented systems for solid-state NMR …

Lipid-nanodiscs have been shown to be an exciting innovation as a membrane-mimicking
system for studies on membrane proteins by a variety of biophysical techniques, including …

Abstract Development of a robust, uniform, and magnetically orientable lipid mimetic will
undoubtedly advance solid-state NMR of macroscopically aligned membrane proteins …

We have used cryo-transmission electron microscopy (cryo-TEM) for inspection of
aggregates formed by dimyristoylphosphatidylcholine (DMPC) and …