Background: Family history provides important information on risk of developing
inflammatory bowel disease [IBD], and genetic profiling of first-degree relatives [FDR] of …

Background Crohn's disease (CD) and ulcerative colitis (UC) are two major forms of
inflammatory bowel disease (IBD). Meta-analyses of genome-wide association studies …

Background & Aims: There is evidence for the IBD1 Crohn's disease (CD) susceptibility
locus on chromosome 16 in several but not all populations studied. Genetic and phenotypic …

Abstract Background and Aim Family history is the strongest risk factor for developing
Crohn's disease [CD] or ulcerative colitis [UC]. We investigated whether the proximity of …

OBJECTIVES: Crohn's disease (CD) and ulcerative colitis (UC) are chronic immunologically
mediated diseases with a progressive relapsing remitting course. There is considerable …

Chronic inflammatory bowel disease (IBD) presents as two major clinical forms, Crohn's
disease (CD) and ulcerative colitis (UC). Genetic epidemiological studies and animal …

Objective Through genome-wide association scans and meta-analyses thereof, over 70
genetic loci (Crohn's disease (CD) single nucleotide polymorphisms (SNPs)) are …

Background While progress has been made in the identification of Crohn's disease (CD)
susceptibility loci, efforts to identify a genetic basis for disease progression have been less …

Background & Aims Relatives of individuals with Crohn's disease (CD) carry CD-associated
genetic variants and are often exposed to environmental factors that increase their risk for …

Inflammatory bowel diseases (IBDs) are complex, multifactorial disorders characterized by
chronic relapsing intestinal inflammation. Although etiology remains largely unknown, recent …