Iatrogenic nerve injury is a common complication across all surgical specialties. Better nerve
visualization and identification during surgery will improve outcomes and reduce nerve …

Nerves are extremely difficult to identify and are often accidently damaged during surgery,
leaving patients with lasting pain and numbness. Herein, a novel near‐infrared (NIR) nerve …

Barth OSA Paper File Final Page 1 Lead Optimization of Nerve-Specific Fluorophores for
Image-Guided Nerve Sparing Surgical Procedures Connor W. Barth1, Lei G. Wang2,Antonio …

Objective: This review details the agents for fluorescence-guided nerve imaging in both
preclinical and clinical use to identify factors important in selecting nerve-specific fluorescent …

Background Accidental peripheral nerve injury during surgical intervention results in a broad
spectrum of potentially debilitating side effects. Tissue distortion and poor visibility can …

Iatrogenic nerve injury represents one of the most feared surgical complications and
remains a major morbidity across many surgical specialties. Currently, no clinically …

The ability to visualize and spare nerves during surgery is critical for avoiding chronic
morbidity, pain, and loss of function. Visualization of such critical anatomic structures is even …

Iatrogenic nerve injury significantly affects surgical outcomes. Although intraoperative
neuromonitoring is utilized, nerve identification remains challenging and the success of …

Nerve-binding fluorophores with near-infrared (NIR; 650 to 900 nm) emission could reduce
iatrogenic nerve injury rates by providing surgeons precise, real-time visualization of the …

Nerve damage is a major morbidity associated with numerous surgical interventions. Yet,
nerve visualization continues to challenge even the most experienced surgeons. A nerve …