Captopril enhances cardiac vagal but not sympathetic neurotransmission in pithed rats

Y Takata, T Arai, S Suzuki, J Kurihara, T Uezono… - Journal of …, 2004 - Elsevier
The effect of captopril on neurally evoked bradycardia and tachycardia was investigated in
pithed rats. Captopril enhanced the vagal nerve stimulation-evoked bradycardia …

Captopril interferes with neurogenic vasoconstriction in the pithed rat by angiotensin-dependent mechanisms

R Hatton, DP Clough - Journal of Cardiovascular Pharmacology, 1982 - journals.lww.com
Angiotensin is known to facilitate the activity of the sympathetic nervous system, and the
purpose of the present study was to investigate the possibility that angiotensin converting …

A facilitatory effect of anti‐angiotensin drugs on vagal bradycardia in the pithed rat and guinea‐pig

M Rechtman, H Majewski - British journal of pharmacology, 1993 - Wiley Online Library
1 In pithed rats, preganglionic vagal nerve stimulation (at 5 Hz) elicited a bradycardia. This
bradycardia was potentiated by the angiotensin converting enzyme inhibitor, captopril (1 mg …

Hypotensive effect of clonidine is not mediated by enhanced baroreflex gain in rats

L Watkins, W Maixner - Journal of cardiovascular pharmacology, 1993 - journals.lww.com
We wished to examine whether enhanced depressor baroreflexes contribute to the
hypotensive effect of clonidine in rats. Clonidine's hypotensive effect and clonidine's effect …

Endogenous angiotensin II facilitates sympathetically mediated hemodynamic responses in pithed rats.

LJ Kaufman, RR Vollmer - Journal of Pharmacology and Experimental …, 1985 - ASPET
The influence of endogenous angiotensin II on the hemodynamic responses to electrical
stimulation of the sympathetic outflow was assessed in pithed male normotensive Wistar rats …

Effects of captopril on [3H]-norepinephrine release in rat central nervous system.

K Tsuda, S Tsuda, I Nishio, Y Masuyama… - Clinical and …, 1995 - europepmc.org
1. The present study was performed to investigate the effects of captopril (an angiotensin
converting enzyme inhibitor, ACE-I) on noradrenergic transmission in the rat central nervous …

Aconitine induces bradycardia through a transmission pathway including the anterior hypothalamus in conscious mice

I Kimura, M Takada, H Nojima - Biological and Pharmaceutical …, 1997 - jstage.jst.go.jp
Aconitine administered intraperitoneally (ip) produces bradycardia mainly by a central
muscarinic action. The involvement of hypothalamic regions in the occurrence of aconitine …

Peripheral presynaptic facilitatory effect of angiotensin II on noradrenaline release in anesthetized rabbits

B Szabo, L Hedler, C Schurr… - Journal of cardiovascular …, 1990 - journals.lww.com
The function of presynaptic angiotensin II receptors at postganglionic sympathetic terminal
axons under conditions of uninterrupted sympathetic impulse traffic was studied in …

Endogenous tachykinins cause bradycardia by stimulating cholinergic neurons in the isolated guinea pig heart

Y Chang, DB Hoover… - American Journal of …, 2000 - journals.physiology.org
The purpose of this study was to determine if endogenous tachykinins can cause
bradycardia in the isolated perfused guinea pig heart through stimulation of cholinergic …

Differential prejunctional effect of captopril and saralasin on neurogenic vasoconstriction in pithed normotensive rats

A De Jonge, B Wilffert, MJMC Thoolen… - Life sciences, 1984 - Elsevier
The present study describes a differential inhibitory effect of captopril and (Sar 1 Ala 8)
angiotensin II (saralasin) on the neurogenic vasoconstriction in pithed normotensive rats. In …