[HTML][HTML] Therapeutic Drug Monitoring and Pharmacokinetics-Based Individualization of Drug Therapy

GB Karvaly, B Vásárhelyi - Pharmaceutics, 2024 - mdpi.com
The philosophy, practice, and clinical impact of therapeutic drug monitoring (TDM) has
changed profoundly with the appearance of widely available and, in a technical sense …

Therapeutic drug monitoring for tomorrow

E Eliasson, JD Lindh, RE Malmström, O Beck… - European journal of …, 2013 - Springer
Therapeutic drug monitoring (TDM) represents an early approach to personalised medicine.
It helps the clinician to individualise drug treatment and guide dosage to reach systemic …

Artificial intelligence and machine learning approaches to facilitate therapeutic drug management and model-informed precision dosing

EA Poweleit, AA Vinks, T Mizuno - Therapeutic drug monitoring, 2023 - journals.lww.com
Background: Therapeutic drug monitoring (TDM) and model-informed precision dosing
(MIPD) have greatly benefitted from computational and mathematical advances over the …

Therapeutic drug monitoring as a component of personalized medicine: applications in pediatric drug development

JD Momper, JA Wagner - Clinical Pharmacology & …, 2014 - Wiley Online Library
Therapeutic drug monitoring (TDM) is foundational to the concept of personalized medicine.
TDM transformed drug therapy by affording the ability to characterize sources of variability in …

Overview of therapeutic drug monitoring

W Clarke - Clinical Challenges in Therapeutic Drug Monitoring, 2016 - Elsevier
Therapeutic drug monitoring (TDM) is a key component of patient management for a select
group of drugs that demonstrate significant interindividual variability in their …

Therapeutic Drug Monitoring in the Era of Precision Medicine: Achievements, Gaps, and Perspectives—An Interview in Honor of Professor Charles Pippenger

SH Wong, P Marquet, D Cattaneo… - Therapeutic Drug …, 2021 - journals.lww.com
In recent years, health care professionals have witnessed a fascinating progress in the
development of new high-throughput technologies, such as third-generation sequencing …

[HTML][HTML] Broader implications of modeling and simulation (M&S) tools in pharmacotherapeutic decisions: a cautionary optimism

A Chaturvedula, BN Palasik, HJ Cho… - Frontiers in …, 2020 - frontiersin.org
While not an entirely new concept, emergence of precision medicine has been catalyzed by
the National Institutes of Health (NIH)'s “Precision Medicine Initiative”(Collins and Varmus …

[HTML][HTML] Therapeutic drug monitoring (TDM): A useful tool for pediatric pharmacology applied to routine clinical practice

R Simeoli, TPC Dorlo, LM Hanff… - Frontiers in …, 2022 - frontiersin.org
1 Background For many therapeutic areas in modern medicine, precision medicine is the
current treatment paradigm. Interestingly, or probably disappointingly, the concept of …

[HTML][HTML] Emerging therapeutic drug monitoring technologies: considerations and opportunities in precision medicine

WS Liang, B Beaulieu-Jones, S Smalley… - Frontiers in …, 2024 - frontiersin.org
In recent years, the development of sensor and wearable technologies have led to their
increased adoption in clinical and health monitoring settings. One area that is in early, but …

Improving therapeutic decisions: pharmacodynamic monitoring as an integral part of therapeutic drug monitoring

M Shipkova, U Christians - Therapeutic drug monitoring, 2019 - journals.lww.com
Although the monitoring of drug therapies based on the determination of drug
concentrations in biological materials is certainly an important instrument for individualized …