Substrate-initiated synthesis of cell-penetrating poly (disulfide) s
EK Bang, G Gasparini, G Molinard, A Roux… - Journal of the …, 2013 - ACS Publications
Lessons from surface-initiated polymerization are applied to grow cell-penetrating poly
(disulfide) s directly on substrates of free choice. Reductive depolymerization after cellular …
(disulfide) s directly on substrates of free choice. Reductive depolymerization after cellular …
Cellular uptake of substrate-initiated cell-penetrating poly (disulfide) s
G Gasparini, EK Bang, G Molinard… - Journal of the …, 2014 - ACS Publications
Substrate-initiated, self-inactivating, cell-penetrating poly (disulfide) s (siCPDs) are
introduced as general transporters for the covalent delivery of unmodified substrates of free …
introduced as general transporters for the covalent delivery of unmodified substrates of free …
Single-molecule kinetics of growth and degradation of cell-penetrating poly (disulfide) s
GS Pulcu, NS Galenkamp, Y Qing… - Journal of the …, 2019 - ACS Publications
The delivery of therapeutic agents into target cells is a challenging task. Cell penetration and
intracellular targeting were recently addressed with biodegradable cell-penetrating poly …
intracellular targeting were recently addressed with biodegradable cell-penetrating poly …
Protein delivery with cell-penetrating poly (disulfide) s
G Gasparini, S Matile - Chemical Communications, 2015 - pubs.rsc.org
Protein delivery with cell-penetrating poly(disulfide)s - Chemical Communications (RSC
Publishing) DOI:10.1039/C5CC07460F Royal Society of Chemistry View PDF VersionPrevious …
Publishing) DOI:10.1039/C5CC07460F Royal Society of Chemistry View PDF VersionPrevious …
Cell-penetrating poly (disulfide) s: the dependence of activity, depolymerization kinetics and intracellular localization on their length
N Chuard, G Gasparini, A Roux, N Sakai… - Organic & biomolecular …, 2015 - pubs.rsc.org
We report that the depolymerization kinetics of cell-penetrating poly (disulfide) s depend
exclusively on their length and propose a kinetic uptake model to explain why their …
exclusively on their length and propose a kinetic uptake model to explain why their …
Intracellular delivery of functional proteins and native drugs by cell-penetrating poly (disulfide) s
The efficient delivery of bioactive compounds into cells is a major challenge in drug
discovery. We report herein the development of novel methods for intracellular delivery of …
discovery. We report herein the development of novel methods for intracellular delivery of …
Poly (disulfide) s: from synthesis to drug delivery
Bioresponsive polymers have been widely used in drug delivery because of their
degradability. For example, poly (disulfide) s with repeating disulfide bonds in the main …
degradability. For example, poly (disulfide) s with repeating disulfide bonds in the main …
Cryopolymerization of 1, 2-dithiolanes for the facile and reversible grafting-from synthesis of protein–polydisulfide conjugates
Grafting-from (GF) is an important yet underdeveloped strategy toward protein–polymer
conjugates. Here, we report a simple cryopolymerization method that enables highly efficient …
conjugates. Here, we report a simple cryopolymerization method that enables highly efficient …
Controlled and Regioselective Ring-Opening Polymerization for Poly (disulfide) s by Anion-Binding Catalysis
T Du, B Shen, J Dai, M Zhang, X Chen… - Journal of the …, 2023 - ACS Publications
Poly (disulfide) s are an emerging class of sulfur-containing polymers with applications in
medicine, energy, and functional materials. However, the constituent dynamic covalent S–S …
medicine, energy, and functional materials. However, the constituent dynamic covalent S–S …
Architecture-controlled ring-opening polymerization for dynamic covalent poly (disulfide) s
A strategy is reported for controlling the architecture of poly (disulfide) s by ring-opening
polymerization. Aryl thiol initiators shift the ring–chain equilibrium to yield cyclic polymers …
polymerization. Aryl thiol initiators shift the ring–chain equilibrium to yield cyclic polymers …
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- synthesis of protein polydisulfide conjugates
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