Rheumatoid arthritis (RA) is a severe inflammatory autoimmune disease affecting
approximately 1% of the world's population and glucocorticoids (GCs) are still among the …

Background Glucocorticoid (GC) therapy is frequently used to treat rheumatoid arthritis due
to potent anti-inflammatory actions of GCs. Direct actions of GCs on immune cells were …

Owing to their anti-inflammatory effects, steroid therapy using glucocorticoids (GCs) is still
part of the treatment of rheumatoid arthritis (RA), despite several severe side effects like …

Results: Mice lacking GR and with hampered GR dimerization capacity in all cell types but
with intact GR in the hematopoietic compartment including circulating immune cells, showed …

Rheumatoid arthritis (RA) is a chronic inflammatory ailment that is characterized by the
hyperproliferative and invasive nature of fibroblast-like synoviocytes (FLS). Although …

Abstract Objective Glucocorticoids (GCs) exert their antiinflammatory and
immunosuppressive effects in humans primarily via the cytosolic GC receptor (cGR) but also …

Background Glucocorticoids are among the most commonly used anti-inflammatory and
immunosuppressive drugs in the treatment of rheumatic diseases. They exert their anti …

Despite several side effects, glucocorticoids (GCs) have been widely used for 60 y to treat
rheumatoid arthritis on the basis of their antiinflammatory effects. However, the cells targeted …

Glucocorticoids (GCs) are widely used to treat chronic inflammatory diseases such as
rheumatoid (RA) and lead to multiple side effects including glucocorticoid induced …

Glucocorticoids (GCs) are widely used to treat chronic inflammatory diseases such as
rheumatoid (RA) and lead to multiple side effects including GC induced osteoporosis (GIO) …