Background: Cigarette smoking is associated with increased head and neck cancer (HNC)
risk. Tobacco-related carcinogens are known to cause bulky DNA adducts. Nucleotide …

Cigarette smoking is the major cause of cancers of the respiratory tract, including non‐small
cell lung cancer (NSCLC) and head and neck cancer (HNC). In order to better understand …

Background The aim of this study was to analyze genetic alterations in the transformation‐
progression model of laryngeal tumors. Methods Copy number changes of 37 genes were …

This review aims to explore the genetic mechanisms involved in the development of
squamous cell carcinoma of the head and neck (SCCHN). The epidemiology of SCCHN is …

DNA repair mechanisms allow maintain genomic stability and proper functioning within the
cells. Any aberrations may cause an increased risk of many diseases such as cancer. The …

Background The genetic profile for human papilloma virus positive (HPV+) oropharyngeal
squamous cell carcinomas (OPSCC) remains largely unknown. The purpose of this study …

Polymorphisms in the selected genes controlling carcinogen metabolism (CYP1A1,
CYP2D6, CYP2E1, NAT2, GSTM1, GSTT1) considered separately or in different …

Squamous-cell cancer of the head and neck (SCCHN) represents a heterogeneous disease
entity, with various etiological factors implicated in the genesis of distinct molecular subsets …

We investigated how somatic changes in HNSCC interact with environmental and host risk
factors and whether they influence the risk of HNSCC occurrence and outcome. 180-paired …

Head and neck squamous cell carcinoma (HNSCC) is a cancer with well-defined tumor
causes such as HPV infection, smoking and drinking. Using The Cancer Genome Atlas …