Molecular pathology of thyroid tumours of follicular cells: a review of genetic alterations and their clinicopathological relevance

G Acquaviva, M Visani, A Repaci, KJ Rhoden… - …, 2018 - Wiley Online Library
Thyroid cancer is the most common endocrine malignancy. Knowledge of the molecular
pathology of thyroid tumours originating from follicular cells has greatly advanced in the past …

ENDOCRINE TUMOURS: Advances in the molecular pathogenesis of thyroid cancer: lessons from the cancer genome

G Riesco-Eizaguirre… - European journal of …, 2016 - academic.oup.com
Thyroid cancer is the most common endocrine malignancy giving rise to one of the most
indolent solid cancers, but also one of the most lethal. In recent years, systematic studies of …

Molecular pathology of thyroid cancer: diagnostic and clinical implications

JA Fagin, N Mitsiades - Best practice & research Clinical endocrinology & …, 2008 - Elsevier
There is now a reasonably good understanding of the key oncogenic events involved in the
initiation and progression of thyroid cancer. Many of these are characteristic of certain tumor …

[PDF][PDF] Molecular pathology of differentiated thyroid cancer

A Greco, MG Borrello, C Miranda… - Quarterly Journal of …, 2009 - researchgate.net
Thyroid cancer is the most common endocrine malignancy; it accounts for approximately 1%
of all new case of cancer each year, and its incidence has increased significantly over the …

[HTML][HTML] Update on fundamental mechanisms of thyroid cancer

A Prete, P Borges de Souza, S Censi… - Frontiers in …, 2020 - frontiersin.org
The incidence of thyroid cancer (TC) has increased worldwide over the past four decades.
TC is divided into three main histological types: differentiated (papillary and follicular TC) …

[HTML][HTML] Influencers on thyroid cancer onset: molecular genetic basis

B Luzón-Toro, RM Fernández, L Villalba-Benito… - Genes, 2019 - mdpi.com
Thyroid cancer, a cancerous tumor or growth located within the thyroid gland, is the most
common endocrine cancer. It is one of the few cancers whereby incidence rates have …

Molecular pathobiology of thyroid neoplasms

G Tallini - Endocrine Pathology, 2002 - Springer
Tumors of thyroid follicular cells provide a very interesting model to understand the
development of human cancer. It is becoming apparent that distinct molecular events are …

[HTML][HTML] Genomic and epigenomic profile of thyroid cancer

A Acuña-Ruiz, C Carrasco-López… - Best Practice & Research …, 2023 - Elsevier
Thyroid cancer is the most common malignancy of the endocrine system, and its incidence
has been steadily increasing. Advances in sequencing have allowed analysis of the entire …

[HTML][HTML] Gene expression profile of human thyroid cancer in relation to its mutational status

D Rusinek, S Szpak-Ulczok… - Journal of molecular …, 2011 - jme.bioscientifica.com
This review describes the gene expression profile changes associated with the presence of
different mutations that contribute to thyroid cell carcinogenesis. The results are discussed in …

[HTML][HTML] Mutations of the TERT promoter are associated with aggressiveness and recurrence/distant metastasis of papillary thyroid carcinoma

R Liu, Y Li, W Chen, J Cong, Z Zhang… - Oncology …, 2020 - spandidos-publications.com
Several previous studies have shown that mutations in B‑Raf proto‑oncogene (BRAF) and
telomerase reverse transcriptase (TERT) can be used for the diagnosis and prognosis of …