Derived from follicular epithelial cells, differentiated thyroid cancer (DTC) accounts for the
majority of thyroid malignancies. The threefold increase in DTC incidence over the last three …

Papillary thyroid cancers are the most common thyroid malignancy. They usually carry a
favorable prognosis, although patients with invasive or metastatic tumors that no longer trap …

Over the past 20 years, our understanding of the molecular biology of thyroid cancer has
advanced significantly. These new insights have in turn unleashed a vast potential for …

A number of molecular abnormalities have been described in association with the
progression from normal thyroid tissue to benign adenomas to well-differentiated and finally …

The incidence of thyroid cancer is rapidly increasing, mostly due to the overdiagnosis and
overtreatment of differentiated thyroid cancer (TC). The increasing use of potent preclinical …

Differentiated thyroid cancer, which includes papillary and follicular histologies, is a common
malignancy and is increasing in incidence. It carries a favorable prognosis compared to …

The morbidity of thyroid cancer is increasing gradually year by year, showing an increasing
tendency in nationality, sex, age, tumor size, and tumor staging. The changes of thyroid cell …

Four types of thyroid cancer comprise more than 98% of all thyroid malignancies. Papillary
thyroid carcinoma (PTC) may have a very benign course while undifferentiated thyroid …

There have been significant advances in our understanding of carcinogenesis at the
molecular level over the last 25 years. Oncogenes are of major interest as part of our search …

Next-generation sequencing (NGS) for molecular diagnostics allows simultaneous testing of
activating oncogenes and tumor suppressor mutations in multiple signal pathways …