The “next-generation” knowledge of papillary thyroid carcinoma

V Costa, R Esposito, P Pallante, A Ciccodicola… - Cell Cycle, 2015 - Taylor & Francis
The application of Next-Generation Sequencing for studying the genetics of papillary thyroid
carcinomas (PTC) has recently revealed new somatic mutations and gene fusions as …

The prognostic implications from molecular testing of thyroid cancer

OB Ozgursoy, DW Eisele… - Otolaryngologic Clinics of …, 2014 - oto.theclinics.com
Thyroid cancer is the most common endocrine malignancy and accounts for approximately
1% of all newly diagnosed cancers. A significant worldwide increase in the incidence of …

[HTML][HTML] Thyroid cancer staging and genomics

AR Shaha, RM Tuttle - Annals of Translational Medicine, 2019 - ncbi.nlm.nih.gov
Kim et al. have published a very interesting article in World Journal of Surgery about staging
of thyroid cancer and implications of genomic analysis based on patients' age (1). The …

[HTML][HTML] Molecular pathogenesis of follicular cell derived thyroid cancers

R Parameswaran, S Brooks, GP Sadler - International Journal of Surgery, 2010 - Elsevier
Thyroid cancers are the most common endocrine malignancy. Radiation exposure, family
history of thyroid cancer and some inherited conditions are the most important predisposing …

[HTML][HTML] Multi-targeted approach in the treatment of thyroid cancer

B Zarebczan, H Chen - Minerva chirurgica, 2010 - ncbi.nlm.nih.gov
Thyroid cancer is the most common malignancy of the endocrine system. There are several
variants, ranging from well-differentiated cancers, such as papillary carcinomas, to poorly …

Oncogenes and thyroid cancer

G Vecchio, M Santoro - 2000 - degruyter.com
Human thyroid tumors can be derived either from epithelial follicular cells or from
parafollicular C-cells. Follicular cell-derived tumors represent a wide spectrum of lesions …

Thyroid cancer: prognostic factors and treatment

LS Ward, LVM Assumpção - Arquivos Brasileiros de Endocrinologia & …, 2004 - SciELO Brasil
Como a maior parte dos carcinomas diferenciados tem um excelente prognóstico, alguns
autores têm considerado o tratamento convencional, isto é, a tiroidectomia total seguida de …

[HTML][HTML] Molecular targeted therapies of aggressive thyroid cancer

SM Ferrari, P Fallahi, U Politti, G Materazzi… - Frontiers in …, 2015 - frontiersin.org
Differentiated thyroid carcinomas (DTCs) that arise from follicular cells account> 90% of
thyroid cancer (TC)[papillary thyroid cancer (PTC) 90%, follicular thyroid cancer (FTC) 10%] …

Molecular targets of tyrosine kinase inhibitors in thyroid cancer

P Fallahi, SM Ferrari, MR Galdiero, G Varricchi… - Seminars in cancer …, 2022 - Elsevier
Thyroid cancer (TC) is the eighth most frequently diagnosed cancer worldwide with a rising
incidence in the past 20 years. Surgery is the primary strategy of therapy for patients with …

[HTML][HTML] Thyroid carcinoma: phenotypic features, underlying biology and potential relevance for targeting therapy

J Hu, IJ Yuan, S Mirshahidi, A Simental, SC Lee… - International journal of …, 2021 - mdpi.com
Thyroid carcinoma consists a group of phenotypically heterogeneous cancers. Recent
advances in biological technologies have been advancing the delineation of genetic …