The role of microglia in retinal inflammation is still ambiguous. Branch retinal vein occlusion
initiates an inflammatory response whereby resident microglia cells are activated. They …

Purpose: To characterize retinal microglia activation and macrophage recruitment in
experimental branch retinal vein occlusion (BRVO). Methods: Experimental BRVO was …

Microglia, the resident phagocytes of the retina, are believed to influence the development of
retinopathy, but their exact contributions to vascular integrity and neuronal loss are …

Background To decipher the role of monocyte-derived macrophages (Mφs) in vascular
remodeling of the occluded vein following experimental branch retinal vein occlusion …

Purpose Retinal vein occlusion (RVO) is a sight-threatening condition typically treated with
intravitreal injection of vascular endothelial growth factor (VEGF) antagonists. Treatment …

Background Microglia-associated inflammation is closely related to the pathogenesis of
various retinal diseases such as uveitis and diabetic retinopathy, which are associated with …

The mechanisms of neuronal degeneration and associated acute alterations in intraretinal
cytokine and protein levels remain poorly understood in variable ischaemic retinopathies …

Background Several retinal pathologies exhibit both inflammation and breakdown of the
inner blood-retinal barrier (iBRB) resulting in vascular permeability, suggesting that …

Microglia are the primary resident retinal macrophages that monitor neuronal activity in real-
time and facilitate angiogenesis during retinal development. In certain retinal diseases, the …

We aim to understand the link between systemic and intraocular levels of inflammatory
mediators in treatment-naïve retinal vein occlusion (RVO) patients, and the relationship …