Synopsis Ganciclovir is a nucleoside analogue with antiviral activity in vitro against
members of the herpes group and some other DNA viruses. It has demonstrated efficacy …

Synopsis The antiviral nucleoside analogue ganciclovir has demonstrated in vitro activity
against human cytomegalovirus and effectively treats infection caused by this organism in …

Ganciclovir is a nucleoside analog which inhibits the replication of herpesviruses in vitro and
which has been effective by intravenous administration for the treatment of severe …

Abstract Ganciclovir (9-[(1, 3-dihydroxy-2-propoxy) methyl] guanine) is a potent inhibitor of
viruses of the herpes family, including cytomegalovirus (CMV), that are pathogenic for …

Ganciclovir is a congener of acyclovir with in vitro activity against cytomegalovirus. Ninety-
seven patients with the acquired immune deficiency syndrome (AIDS) and a serious …

Ganciclovir is a nucleoside guanosine analogue which incorporates ganciclovir
triphosphate (the active moiety) into DNA during elongation, thereby inhibiting viral …

A total of 314 immunocompromised patients with serious cytomegalovirus (CMV) infection
treated with ganciclovir administered intravenously were studied. Rates of favorable clinical …

The pharmacokinetics of ganciclovir was evaluated in 21 patients with life-or sight-
threatening cytomegalovirus infections. Thirteen patients had normal renal function and …

Ganciclovir and foscarnet possess substantial activity against cytomegalovirus. Both exhibit
dose-limiting toxicity, which reduces their clinical usefulness. We demonstrated synergistic …

Thirty-one immunocompromised patients with severe cytomegalovirus (CMV) disease were
treated with intravenous ganciclovir. Twenty-one patients had received transplants—15 …