Expanding roles of superoxide dismutases in cell regulation and cancer

M Che, R Wang, X Li, HY Wang, XFS Zheng - Drug discovery today, 2016 - Elsevier
Highlights•Superoxide dismutases (SODs) have important regulatory functions in
metabolism, signalling and transcription.•SODs are crucial for cancer cell growth …

Reevaluation of assay methods and establishment of kit for superoxide dismutase activity

Y Ōyanagui - Analytical biochemistry, 1984 - Elsevier
Superoxide dismutase (SOD) activity was measured by seven assay methods. The nitrite
method was found to be the best for our SOD assay kit. This method was then modified to …

Cross-linked antioxidant nanozymes for improved delivery to CNS

NL Klyachko, DS Manickam, AM Brynskikh… - … , biology and medicine, 2012 - Elsevier
Formulations of antioxidant enzymes, superoxide dismutase 1 (SOD1, also known as Cu/Zn
SOD) and catalase were prepared by electrostatic coupling of enzymes with cationic block …

Therapeutic potential of superoxide dismutase mimetics as therapeutic agents in critical care medicine

D Salvemini, S Cuzzocrea - Critical care medicine, 2003 - journals.lww.com
Oxidative stress results from an oxidant/antioxidant imbalance, an excess of oxidants, or a
depletion of antioxidants. A considerable body of recent evidence suggests that oxidative …

Manganese superoxide dismutase in disease

LA Macmillan-Crow, DL Cruthirds - Free radical research, 2001 - Taylor & Francis
Manganese superoxide dismutase (MnSOD) is essential for life as dramatically illustrated by
the neonatal lethality of mice that are deficient in MnSOD. In addition, mice expressing only …

[HTML][HTML] Superoxide: a two-edged sword

BM Babior - Brazilian Journal of Medical and Biological Research, 1997 - SciELO Brasil
Superoxide (O2-) is the compound obtained when oxygen is reduced by one electron. For a
molecule with an unpaired electron, O2-is surprisingly inert, its chief reaction being a …

Oxidative stress in disease and aging: mechanisms and therapies 2016

C Cabello-Verrugio, F Simon… - Oxidative medicine …, 2016 - hal.sorbonne-universite.fr
Oxidative stress (OS) is an imbalance between the formation of reactive oxygen species
(ROS) and antioxidant defense mechanisms. This phenomenon increases with age and …

Human extracellular superoxide dismutase is a tetramer composed of two disulphide-linked dimers: a simplified, high-yield purification of extracellular superoxide …

TD Oury, JD CRAPO, Z VALNICKOVA… - Biochemical …, 1996 - portlandpress.com
Studies examining the biochemical characteristics and pharmacological properties of
extracellular superoxide dismutase (EC SOD) have been severely limited because of …

Scientific basis for the clinical use of superoxide dismutase

A Petkau - Cancer Treatment Reviews, 1986 - Elsevier
In a recent review of chemical carcinogenesis, Kensler and Trush (157) express the hope
'that an evaluation of the importance of oxygen free radicals in chemical carcinogenesis will …

[引用][C] Assays for superoxide dismutase

JV Bannister, L Calabrese - Methods of biochemical analysis, 1987 - Wiley Online Library
Assays for Superoxide Dismutase Page 1 ~ METHODS OF BIOCHEMICAL ANALYSIS VOLUME
32 Assays for Superoxide Dismutase JOE v. BANNISTER, Biotechnology Centre, Cranfield …