Ischemic heart disease (IHD) is the major cause of morbidity and mortality all over the world.
World health organization (WHO) in 2002 assumed that IHD may be the major leading …

Acute myocardial infarction is caused by a sudden coronary artery occlusion and leads to
ischemia in the corresponding myocardial territory which generally results in myocardial …

Although restoration of blood flow to an ischaemic organ is essential to prevent irreversible
tissue injury, reperfusion per se may result in a local and systemic inflammatory response …

Cardiovascular events are one of the leading causes of death in the world. Thrombolysis,
percutaneous transluminal coronary angioplasty, and coronary bypass surgery are the …

Ischemic myocardium must be reperfused to terminate the ischemic event; otherwise the
entire myocardium involved in the area at risk will not survive. However, there is a cost to …

Lack of blood supply or ischaemia underlies many of the most important cardiovascular and
cerebrovascular diseases faced by clinicians in their daily practice. Many of these ischaemic …

Postischemic reperfusion may profoundly alter cardiac function. Principal mediators of this
phenomenon are oxygen radicals and neutrophils. Upon reflow, oxygen radicals are …

Ischemia-reperfusion (I/R) injury is a manifestation of the acute inflammatory response
initiated by overlapping cascades of inflammatory mediators expressed at both local and …

ST-segment elevation myocardial infarction is a major cause of morbidity and mortality
worldwide. Reperfusion injury (RI) following the opening of an occluded coronary artery …

Abstract Ischemia/reperfusion (I/R) injury is an inflammatory condition that is characterized
by innate immunity and an adaptive immune response. This review is focused on the acute …