Baroreflex sensitization and direct sympatholytic effects have been suggested as
contributing mechanisms to the effects of dihydropyridine calcium channel blockers in …

Calcium channel antagonists differ by class in reported frequency of side effects that suggest
reflex sympathoadrenal activation. Do such differences result from differential effects on …

To investigate the effect of amlodipine on baroreflex sensitivity and sympathetic system
activity, 36 patients with essential hypertension were randomized to once-daily, double-blind …

The effect of dihydropyridine calcium channel blocker (CCB) on baroreflex sensitivity (BRS)
is not well described. We studied the effect of a new CCB, azelnidipine, compared with …

Calcium channel antagonists, when used to treat hypertension, may modulate baroreflex
function and vascular responsiveness to endogenous vasoconstrictors. We studied regional …

It is generally assumed that the arterial vasodilation induced by inhibition of Ca 2+ influx into
vascular smooth muscle cells represents the main mechanism for the hypotensive effect of …

The value of plasma norepinephrine measurement in assessing baroreceptor-mediated
changes in sympathetic vasomotor activity was studied in seven healthy normotensive …

Sympathetic nerve activity is augmented by calcium-channel blocker treatment as a result of
decreased blood pressure. Dihydropyridine calcium-channel blockers are divided into three …

Objectives Calcium antagonists are vasodilating drugs, which may cause reflex activation of
the sympathetic nervous system with potentially untoward effects. We studied the effects of …

Studies in animals have demonstrated that calcium channel blocking agents exert important
influences on autonomic mechanisms in addition to their direct vascular effects. Previous …