The total population of muscarinic receptors and a subpopulation of muscarinic receptors
with high affinity for agonists were measured with [3 H] quinuclidinyl benzilate and [3 H] …

The cholinergic receptors are classically divided into two kinds, namely the nicotinic
acetylcholine receptor and the muscarinic acetyl-choline receptor. The existence of these …

The cellular distribution of muscarinic acetylcholine receptor protein in the frontal cortex of
Alzheimer (AD) patients, age-matched and middle-aged controls was assessed …

Neurochemical studies on human brains obtained at autopsy have over the past two
decades contributed much to our understanding of the role of distinct neurotransmitter …

Cholinergic receptors (muscarinic subtypes M1 and M2, and putative nicotinic binding) have
been examined in the hippocampus obtained at autopsy from a variety of patients with …

Nicotinic cholinergic receptors were measured in human frontal cortex using [3 H] nicotine
and [3 H] acetylcholine (in the presence of atropine) as receptor ligands. A parallel marked …

Different effects of normal aging on muscarinic and nicotinic receptor subtypes were
observed in postmortem brain tissue from different regions of the human brain. A significant …

Nicotinic and muscarinic cholinergic receptors were studied in autopsied brains from four
histologically normal controls and five histopathologically verified cases of Alzheimer‐type …

Total muscarinic receptor levels, the levels of the subtypes exhibiting high and low affinity for
pirenzepine, and the high‐and low‐affinity agonist states of the receptor were investigated in …

The main objective of the present study was to determine whether cholinergic markers
(choline acetyl‐transferase activity and nicotinic and muscarinic receptors) are altered in …