Adenosine modulates synaptic transmission by acting on inhibitory A1 and facilitatory A2A
receptors, the densities of which are modified in aged animals. We investigated how A2A …

Adenosine either inhibits or facilitates synaptic transmission through A1 or A2A receptors,
respectively. Since A2A receptor density increases in the limbic cortex of aged (24 mo) …

Adenosine A 2a receptors are not confined to dopamine-rich areas of the brain, since
thermocycling analysis shows that adenosine A 2a receptor mRNA is expressed also in the …

Adenosine is a neuromodulator in the hippocampus acting mainly via inhibitory A1 receptors
but also via facilitatory A2A receptors. We now investigated the transducing system operated …

The adenosine A3 receptor is expressed in brain, but the consequences of activation of this
receptor on electrophysiological activity are unknown. We have characterized the actions of …

Previous work has been carried out on the effects of adenosine on transmitter release and
on the excitability of postsynaptic neurones, but little is known about the effects of adenosine …

Adenosine tonically inhibits synaptic transmission through actions at A1 receptors. It also
facilitates synaptic transmission, but it is unclear if this facilitation results from pre-and/or …

Intracellular recordings were made in rat brain slice preparations containing pyramidal cells
of the associative frontal cortex in order to characterize the action of selective adenosine A1 …

In the present study we investigated the role of A2A adenosine receptors in hippocampal
synaptic transmission under in vitro ischaemia‐like conditions. The effects of adenosine, of …

Adenosine A2A receptors are most abundant in the striatum where they control the
striatopallidal pathway thus controlling locomotion. Extra-striatal A2A receptors are …