A four‐gene methylation marker panel as triage test in high‐risk human papillomavirus positive patients
JJH Eijsink, A Lendvai, V Deregowski… - … journal of cancer, 2012 - Wiley Online Library
Cervical neoplasia‐specific biomarkers, eg DNA methylation markers, with high sensitivity
and specificity are urgently needed to improve current population‐based screening on (pre) …
and specificity are urgently needed to improve current population‐based screening on (pre) …
DNA methylation markers as a triage test for identification of cervical lesions in a high risk human papillomavirus positive screening cohort
RW van Leeuwen, A Oštrbenk, M Poljak… - … Journal of Cancer, 2019 - Wiley Online Library
Objective triage strategies are required to prevent unnecessary referrals for colposcopy in
population‐based screening programs using primary high‐risk human papillomavirus …
population‐based screening programs using primary high‐risk human papillomavirus …
Discovery and validation of candidate host DNA methylation markers for detection of cervical precancer and cancer
Human papillomavirus (HPV) testing has been recently introduced as an alternative to
cytology for cervical cancer screening. However, since most HPV infections clear without …
cytology for cervical cancer screening. However, since most HPV infections clear without …
Methylation markers FAM19A4 and miR124‐2 as triage strategy for primary human papillomavirus screen positive women: A large European multicenter study
J Bonde, A Floore, D Ejegod, FJ Vink… - … journal of cancer, 2021 - Wiley Online Library
In human papillomavirus (HPV) cervical cancer screening, cytology is used as triage to
counter the low specificity of HPV testing. VALID‐SCREEN is a EU‐multicenter …
counter the low specificity of HPV testing. VALID‐SCREEN is a EU‐multicenter …
Evaluation of a validated methylation triage signature for human papillomavirus positive women in the HPV FOCAL cervical cancer screening trial
DA Cook, M Krajden, AR Brentnall… - … Journal of Cancer, 2019 - Wiley Online Library
Human papillomavirus (HPV)‐based cervical cancer screening requires triage of HPV
positive women to identify those at risk of cervical intraepithelial neoplasia grade 2 (CIN2) or …
positive women to identify those at risk of cervical intraepithelial neoplasia grade 2 (CIN2) or …
Human papillomavirus DNA methylation as a biomarker for cervical precancer: consistency across 12 genotypes and potential impact on management of HPV-positive …
Abstract Purpose: Human papillomavirus (HPV) DNA methylation testing is a promising
triage option for women testing HPV positive during cervical cancer screening. However, the …
triage option for women testing HPV positive during cervical cancer screening. However, the …
DNA methylation testing with S5 for triage of high‐risk HPV positive women
R Adcock, B Nedjai, AT Lorincz… - … Journal of Cancer, 2022 - Wiley Online Library
Methylation of host and viral genes is promising for triage of women with high‐risk human
papillomavirus infections (hrHPV). Using a population‐based sample of hrHPV positive …
papillomavirus infections (hrHPV). Using a population‐based sample of hrHPV positive …
Development of a multiplex methylation-specific PCR as candidate triage test for women with an HPV-positive cervical scrape
S Snellenberg, LMAD Strooper, AT Hesselink… - BMC cancer, 2012 - Springer
Background Quantitative methylation-specific PCR (qMSP) analysis for determining the
methylation status of (candidate) tumor suppressor genes has potential as objective and …
methylation status of (candidate) tumor suppressor genes has potential as objective and …
A promising DNA methylation signature for the triage of high-risk human papillomavirus DNA-positive women
A Hansel, D Steinbach, C Greinke, M Schmitz, J Eiselt… - PloS one, 2014 - journals.plos.org
High-risk human papillomavirus (hrHPV)-DNA testing is frequently performed parallel to
cytology for the detection of high-grade dysplasia and cervical cancer particularly in women …
cytology for the detection of high-grade dysplasia and cervical cancer particularly in women …
Triage by methylation-marker testing versus cytology in women who test HPV-positive on self-collected cervicovaginal specimens (PROHTECT-3): a randomised …
VMJ Verhoef, RP Bosgraaf, FJ van Kemenade… - The lancet …, 2014 - thelancet.com
Background Cytology is a widely used method of triaging women who test positive for
human papillomavirus (HPV). However, self-sampled specimens, which can substantially …
human papillomavirus (HPV). However, self-sampled specimens, which can substantially …