Integrins are the adhesion molecules and receptors of extracellular matrix (ECM). They
mediate the interactions between cells-cells and cells-ECM. The crosstalk between cancer …

Integrin-mediated adhesion of cells to the extracellular matrix (ECM) is crucial for the
physiological development and functioning of tissues but is pathologically disrupted in …

Cell adhesion to the extracellular matrix is fundamental to tissue integrity and human health.
Integrins are the main cellular adhesion receptors that through multifaceted roles as …

While integrins were originally discovered as cell adhesion receptors, recent studies have
reinforced the concept that integrins have central roles in cancer that extend far beyond …

Interactions with the extracellular matrix (ECM) provide cells with physical and chemical
cues that act in concert with growth factors to support survival and proliferation …

Interactions between cancer cells and their surroundings can trigger essential signaling
cues that determine cell fate and influence the evolution of the malignant phenotype. As the …

Integrins are vital surface adhesion receptors that mediate interactions between the
extracellular matrix (ECM) and cells and are essential for cell migration and the …

Integrins, a group of heterodimer receptors for cell-matrix and cell-cell adhesion, mediate
various intracellular activities, including cell migration, polarity, survival, growth, and death …

Integrins mediate cell adhesion and transmit mechanical and chemical signals to the cell
interior. Various mechanisms deregulate integrin signaling in cancer, empowering tumor …

Integrins mediate adhesive interactions between cells and their environment, including
neighboring cells and extracellular matrix (ECM). These heterodimeric transmembrane …