Rationale: Computed tomography (CT) has been shown to reliably measure the airway wall
dimensions of medium to large airways. Optical coherence tomography (OCT) is a promising …

Airway dimensions are difficult to quantify bronchoscopically because of optical distortion
and a limited ability to gauge depth. Anatomical optical coherence tomography (a OCT), a …

Ever since the site and nature of airflow obstruction in chronic obstructive pulmonary
disease was described by Hogg, Thurlbeck, and Macklem, investigators have been looking …

Flexible bronchoscopy is a common procedure that is used in both diagnostic and
therapeutic settings but does not readily permit measurement of central airway dimensions …

BACKGROUND: Airway remodeling in asthma and COPD results in bronchial wall
thickening. The thickness of the bronchial wall can be measured in high-resolution …

PURPOSE: To design and validate a dedicated software tool to measure airway dimensions
on thin-section computed tomographic (CT) images and to use the tool to prospectively …

Rationale: Our understanding of how airway remodeling affects regional airway elastic
properties is limited due to technical difficulties in quantitatively measuring dynamic, in vivo …

Background: Chronic obstructive pulmonary disease (COPD) is characterized by airflow
obstruction caused by emphysema or airway narrowing, or both. Recently airway …

Airway remodeling is extremely important in the pathophysiology of chronic obstructive
pulmonary disease (COPD). Since the site and nature of airflow obstruction was described …

Bronchial wall area percent (WA%= 100× wall area/total bronchial cross sectional area) is a
standard computed tomographic (CT) measure of central airway morphology utilized in …