Moderate hyperglycemia worsens acute blood-brain barrier injury after forebrain ischemia in rats.

WD Dietrich, O Alonso, R Busto - Stroke, 1993 - Am Heart Assoc
Clinical and experimental data indicate that hyperglycemia can aggravate the
consequences of stroke and cerebral ischemia. The purpose of this study was to examine …

Glutamate‐mediated injury in focal cerebral ischemia: the excitotoxin hypothesis revised

KA Hossmann - Brain Pathology, 1994 - Wiley Online Library
Neuronal injury following focal cerebral ischemia is widely attributed to the excitotoxic effects
of gluta‐mate. However, critical analysis of published data on glutamate toxicity in vitro and …

Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activation

K Fink, J Zhu, S Namura… - Journal of Cerebral …, 1998 - journals.sagepub.com
Apoptotic cell death is prominent in neurodegenerative disorders, such as Alzheimer's
disease and Huntington's disease, and is found in cerebral ischemia. Using a murine model …

Isoflurane prevents delayed cell death in an organotypic slice culture model of cerebral ischemia

BL Sullivan, D Leu, DM Taylor, CS Fahlman… - The Journal of the …, 2002 - pubs.asahq.org
Background General anesthetics reduce neuronal death caused by focal cerebral ischemia
in rodents and by in vitro ischemia in cultured neurons and brain slices. However, in intact …

Cerebral circulation and metabolism

BK Siesjö - Journal of neurosurgery, 1984 - thejns.org
✓ Recent developments in the field of cerebral circulation and metabolism are reviewed,
with emphasis on circulatory and metabolic events that have a bearing on brain damage …

Intravenous anesthetics differentially reduce neurotransmission damage caused by oxygen-glucose deprivation in rat hippocampal slices in correlation with N-methyl …

RZ Zhan, S Qi, C Wu, H Fujihara, K Taga… - Critical care …, 2001 - journals.lww.com
Intravenous anesthetics differentially reduce neurotransmiss... : Critical Care Medicine
Intravenous anesthetics differentially reduce neurotransmission damage caused by oxygen-glucose …

[引用][C] Brain oedema following brain ischaemia and the influence of therapy

I Klatzo - British journal of anaesthesia, 1985 - Elsevier
At the present time, brain oedema is classified into two types: cytotoxicand vasogenic
(Klatzo, 1967) in accordance with two basically different pathological mechanisms involved …

Ischemic brain damage in rats following cardiac arrest using a long-term recovery model

P Blomqvist, T Wieloch - Journal of Cerebral Blood Flow & …, 1985 - journals.sagepub.com
A model is described in which transient complete cerebral ischemia is induced in rats by
intracardiac injection of potassium chloride. The animals were intubated and mechanically …

An intrathecal bolus of cyclosporin A before injury preserves mitochondrial integrity and attenuates axonal disruption in traumatic brain injury

DO Okonkwo, JT Povlishock - Journal of Cerebral Blood …, 1999 - journals.sagepub.com
Traumatic brain injury evokes multiple axonal pathologies that contribute to the ultimate
disconnection of injured axons. In severe traumatic brain injury, the axolemma is perturbed …

Cerebral resuscitation from cardiac arrest: pathophysiologic mechanisms

P Vaagenes, M Ginsberg, U Ebmeyer… - Critical care …, 1996 - journals.lww.com
Both the period of total circulatory arrest to the brain and postischemic-anoxic
encephalopathy (cerebral postresuscitation syndrome or disease), after normothermic …