AQP5 regulates the proliferation and differentiation of epidermal stem cells in skin aging

J Zhou, Y Dong, J Liu, J Ren, J Wu… - Brazilian Journal of …, 2020 - SciELO Brasil
The epidermis, the outermost layer of the skin, is the first barrier that comes into contact with
the external environment. It plays an important role in resisting the invasion of harmful …

Is Aquaporin-3 a determinant factor of intrinsic and extrinsic aging? An immunohistochemical and morphometric study

I Seleit, OA Bakry, HS El Rebey… - Applied …, 2017 - journals.lww.com
Abstract Aquaporin-3 (AQP3) is an aquaglyceroporin that plays a role in skin hydration, cell
proliferation, and migration. The aim of this work was to investigate the expression of AQP3 …

Aquaporin-3 in the epidermis: more than skin deep

WB Bollag, L Aitkens, J White… - American Journal of …, 2020 - journals.physiology.org
The skin is essential for terrestrial life. It is responsible for regulating water permeability and
functions as a mechanical barrier that protects against environmental insults such as …

Aquaporin‐3 gene and protein expression in sun‐protected human skin decreases with skin ageing

J Li, H Tang, X Hu, M Chen… - Australasian journal of …, 2010 - Wiley Online Library
ABSTRACT Backgroud/Objectives: Aquaporin 3 (AQP3) is a protein implicated in skin
hydration. AQP3 null mice have relatively dry skin, reduced skin elasticity, and delayed …

[HTML][HTML] Analysis of aquaporin 9 expression in human epidermis and cultured keratinocytes

Y Sugiyama, K Yamazaki, A Kusaka-Kikushima… - FEBS Open Bio, 2014 - Elsevier
Abstract Aquaporin 9 (AQP9) is a member of the aquaglyceroporin family that transports
glycerol, urea and other small solutes as well as water. Compared to the expression and …

Trans-Zeatin attenuates ultraviolet induced down-regulation of aquaporin-3 in cultured human skin keratinocytes

C Ji, Y Yang, B Yang, J Xia, W Sun… - International …, 2010 - spandidos-publications.com
Solar ultraviolet (UV) irradiation is one of the most significant extrinsic factors contributing to
skin photoaging. One major characteristic of photoaging induced by UV is water loss of the …

[HTML][HTML] Upregulation of aquaporin-3 is involved in keratinocyte proliferation and epidermal hyperplasia

K Nakahigashi, K Kabashima, A Ikoma… - Journal of Investigative …, 2011 - Elsevier
Aquaporin-3 (AQP3) is a water/glycerol-transporting protein expressed in keratinocytes of
the epidermis. We previously showed that AQP3-mediated transport of water and glycerol is …

[HTML][HTML] Aquaporin-3 facilitates epidermal cell migration and proliferation during wound healing

M Hara-Chikuma, AS Verkman - Journal of Molecular Medicine, 2008 - Springer
Healing of skin wounds is a multi-step process involving the migration and proliferation of
basal keratinocytes in epidermis, which strongly express the water/glycerol-transporting …

Relationship between aging-related skin dryness and aquaporins

N Ikarashi, R Kon, M Kaneko, N Mizukami… - International journal of …, 2017 - mdpi.com
Skin function deteriorates with aging, and the dermal water content decreases. In this study,
we have analyzed the mechanism of aging-related skin dryness focusing on aquaporins …

[HTML][HTML] The expression of differentiation markers in aquaporin-3 deficient epidermis

M Hara-Chikuma, K Takahashi, S Chikuma… - Archives of …, 2009 - Springer
Abstract Aquaporin-3 (AQP3) is a water/glycerol transporting protein expressed strongly at
the plasma membrane of keratinocytes. There is evidence for involvement of AQP3 …