[HTML][HTML] The trRosetta server for fast and accurate protein structure prediction

Z Du, H Su, W Wang, L Ye, H Wei, Z Peng… - Nature protocols, 2021 - nature.com
The trRosetta (transform-restrained Rosetta) server is a web-based platform for fast and
accurate protein structure prediction, powered by deep learning and Rosetta. With the input …

Single-sequence protein structure prediction using supervised transformer protein language models

W Wang, Z Peng, J Yang - Nature Computational Science, 2022 - nature.com
Significant progress has been made in protein structure prediction in recent years. However,
it remains challenging for AlphaFold2 and other deep learning-based methods to predict …

GalaxyRefine2: simultaneous refinement of inaccurate local regions and overall protein structure

GR Lee, J Won, L Heo, C Seok - Nucleic acids research, 2019 - academic.oup.com
The 3D structure of a protein can be predicted from its amino acid sequence with high
accuracy for a large fraction of cases because of the availability of large quantities of …

Protein tertiary structure prediction and refinement using deep learning and Rosetta in CASP14

I Anishchenko, M Baek, H Park… - Proteins: Structure …, 2021 - Wiley Online Library
The trRosetta structure prediction method employs deep learning to generate predicted
residue‐residue distance and orientation distributions from which 3D models are built. We …

Improved protein structure prediction using a new multi‐scale network and homologous templates

H Su, W Wang, Z Du, Z Peng, SH Gao… - Advanced …, 2021 - Wiley Online Library
The accuracy of de novo protein structure prediction has been improved considerably in
recent years, mostly due to the introduction of deep learning techniques. In this work …

LOMETS3: Integrating deep learning and profile alignment for advanced protein template recognition and function annotation

W Zheng, Q Wuyun, X Zhou, Y Li… - Nucleic acids …, 2022 - academic.oup.com
Deep learning techniques have significantly advanced the field of protein structure
prediction. LOMETS3 (https://zhanglab. ccmb. med. umich. edu/LOMETS/) is a new …

Analysis of distance‐based protein structure prediction by deep learning in CASP13

J Xu, S Wang - Proteins: Structure, Function, and Bioinformatics, 2019 - Wiley Online Library
This paper reports the CASP13 results of distance‐based contact prediction, threading, and
folding methods implemented in three RaptorX servers, which are built upon the powerful …

Improved protein structure prediction using predicted interresidue orientations

J Yang, I Anishchenko, H Park… - Proceedings of the …, 2020 - National Acad Sciences
The prediction of interresidue contacts and distances from coevolutionary data using deep
learning has considerably advanced protein structure prediction. Here, we build on these …

2 : protein structure prediction server

CC Chen, JK Hwang, JM Yang - Nucleic acids research, 2006 - academic.oup.com
Protein structure prediction provides valuable insights into function, and comparative
modeling is one of the most reliable methods to predict 3D structures directly from amino …

Single-sequence protein structure prediction using a language model and deep learning

R Chowdhury, N Bouatta, S Biswas, C Floristean… - Nature …, 2022 - nature.com
AlphaFold2 and related computational systems predict protein structure using deep learning
and co-evolutionary relationships encoded in multiple sequence alignments (MSAs) …