Intermedilysin is a cytolytic toxin produced by Streptococcus intermedius, a pathogen of
humans. In vitro studies showed that exposure of S. intermedius to sub-minimum inhibitory …

The distribution of intermedilysin, a human-specific cytolysin, among the anginosus group
streptococci and the correlation of toxin production and infection by Streptococcus …

The unique species specificity of the bacterial cytolysin intermedilysin is explained by its
requirement for the human complement regulator CD59 as the primary receptor. Binding …

Streptococcus intermedius is a member of the normal flora of the mouth but is also an
opportunistic pathogen associated with purulent infections at oral and nonoral sites …

Streptococcus intermedius is one of the three distinct species classified into the
Streptococcus milleri-group (SMG, S. anginosus, S. constellatus and S. intermedius) which …

Streptococcus intermedius is an opportunistic bacterial pathogen secreting a human-specific
cytolysin called intermedilysin (ILY) as a major pathogenic factor. This bacterium can …

A novel cytotoxin (intermedilysin) specific for human cells was identified as a cytolytic factor
of Streptococcus intermedius UNS46 isolated from a human liver abscess. Intermedilysin …

Streptococcus intermedius, which causes endogenous infections leading to abscesses,
produces intermedilysin (ILY), a human-specific cytolysin. Because of the significant …

Streptococcus intermedius is an opportunistic pathogen of humans that causes purulent
infections, including brain and liver abscesses. This pathogen secretes a human-specific …

Streptococcus intermedius secretes a human-specific cytolysin, intermedilysin (ILY), which is
considered to be the major virulence factor of this pathogen. We screened for a repressor of …