Hypoxia following arteriovenous fistulization results in venous neointimal hyperplasia
(VNH), potentially causing early arteriovenous fistula (AVF) dysfunction. In this study, we …

Key points Patients with end‐stage renal failure need arteriovenous fistulas (AVF) to
undergo dialysis. However, AVFs present a high rate of failure as a result of excessive …

Hyperbaric oxygen (HBO) is increasingly used in a number of areas of medical practice,
such as selected problem infections and wounds. The beneficial effects of HBO in treating …

Background The poor clinical results that are frequently reported for arteriovenous fistulae
(AVF) for hemodialysis are typically due to failure of AVF maturation. We hypothesized that …

For patients with end-stage renal disease requiring hemodialysis, their vascular access is
both their lifeline and their Achilles heel. Despite being recommended as primary vascular …

Background Numerous mechanisms for the formation of intimal hyperplasia have been
proposed but none have been proven or accepted. Our research focuses on the potential …

Background Neointimal hyperplasia is the main cause of arteriovenous fistula (AVF) failure.
Hypoxia‐inducible factors (HIFs) factors are associated with neointimal hyperplasia. Thus …

BACKGROUND: Venous hypoxia has been postulated to contribute to varicose vein (VV)
formation. Direct measurements of vein wall oxygen tension have previously demonstrated …

BACKGROUND: Doxycycline and micronized purified flavonoid fraction (MPFF) modulate
vein wall remodeling that may be associated with hypoxia in varicose veins (VVs), vein graft …

PURPOSE: A mouse model of renal insufficiency with arteriovenous fistula (AVF) and
venous stenosis was created. The authors tested the hypothesis that there is increased gene …