Using the radioimmunoassay technique for measuring serum digoxin, it was found that
patients who were given 0.25 mg. digoxin orally per day had a mean serum level of …

Digoxin concentmtions in serum and left ventricular tissue were measured at autopsy and
related to estimated antemortem creatinine clearances in 15 patients. A significant …

Digoxin was determined in postmortem serum samples from 100 patients who died
suddenly of cardiac disease. Twenty patients had digoxin levels below the therapeutic …

Tissue distribution and left ventricular (LV) effects of digoxin were studied after intravenous
administration of low and high doses to dogs. LV dP/dt was increased by 0.03 mg/kg digoxin …

Thirty-four dogs were given tritium-labeled digoxin intravenously. Serum and tissue
concentrations and half-times were determined. As demonstrated previously in human …

The tissue concentrations of digoxin were measured in 13 cadavers who before death had
been on the maintenance digoxin therapy. Tissue samples were taken from 5 different parts …

Postmortal tissue digoxin concentration and prefinal and postmortal plasma digoxin
concentrations from 9 patients were determined using the 125J-digoxin radioimmunoassay …

1. Determinations of serum digoxin levels utilizing commercially available kits with an 125I-
labelled antigen were precise and not materially different from results obtained with a 3H …

The criteria which a drug must fulfil before it can be said that it may be worthwhile making
regular plasma concentration measurements of that drug in monitoring therapy are …

A prospective survey of the incidence of digitalis toxicity and its correlation with plasma
digoxin levels determined by radioimmunoassay has failed to show any difference between …