Determination of myocardial and serum digoxin concentrations in children by specific and nonspecific assay methods

JG Wagner, M Dick, DM Behrendt… - Clinical …, 1983 - Wiley Online Library
After obtaining samples at open heart surgery, serum and right atrial digoxin concentrations
were measured in 25 children by a nonspecific, direct radioimmunoassay method (NS) and …

Digoxin concentrations in the serum and myocardium of digitalised patients

PR Carroll, A Gelbart, MF O'Rourke… - Australian and New …, 1973 - Wiley Online Library
In an attempt to evaluate the serum digoxin concentration as a guide to digitalis treatment,
serum and myocardial concentrations were measured in 27 patients undergoing cardiac …

Monitoring digoxin therapy: the use of plasma digoxin concentration measurements in the diagnosis of digoxin toxicity

JK Aronson, DG Grahame-Smith… - QJM: An International …, 1978 - academic.oup.com
The usefulness of measuring plasma digoxin concentrations in the diagnosis of digoxin
toxicity has been assessed in 83 in-patients. The mean plasma digoxin concentration in …

Influence of everyday physical activity on the serum digoxin concentration in digoxin‐treated patients

T Jogestrand - Clinical Physiology, 1981 - Wiley Online Library
Thirteen patients admitted to hospital because of known or suspected cardiac disease who
had been treated with digoxin within, at least, the previous month were investigated. Blood …

Physiological distribution of digoxin in human heart

DJ Coltart, HG Güllner, M Billingham, RH Goldman… - Br Med J, 1974 - bmj.com
Using the recipient's human heart removed at cardiac transplantation, the distribution of
digoxin at both the cellular and subcellular level has been studied. In the presence of diffuse …

Enhanced cardiac effect of digoxin during quinidine treatment

EB Leahey, JA Reiffel, RH Heissenbuttel… - Archives of Internal …, 1979 - jamanetwork.com
Quinidine causes an increase in the serum digoxin concentration. Three patients were
studied to determine if the increase in serum concentration is paralleled by an increase in …

Interactions with digoxin: more problems.

CF George - British Medical Journal (Clinical research ed.), 1982 - ncbi.nlm.nih.gov
Of the several glycosides available for treating heart disease, digoxin has found most favour
in Britain. All these drugs have a narrow therapeutic index, and intoxication occurs in 10 …

Nicardipine does not significantly affect serum digoxin concentrations at the steady state of patients with congestive heart failure.

D Debruyne, P Commeau, G Grollier… - … journal of clinical …, 1989 - europepmc.org
Twenty patients in a stable condition suffering from congestive heart failure were treated with
digoxin for at least three weeks and then with nicardipine concomitantly for five days. No …

Assays of digitalis in the blood

VP Butler Jr - Progress in Cardiovascular Diseases, 1972 - Elsevier
Today, ALMOST TWO CENTURIES after Withering first reported that digitalis “has a power
over the motion of the heart, to a degree yet unobserved in any other medicine,” this …

Plasma and tissue digoxin concentrations in patients undergoing cardiopulmonary bypass.

SG Carruthers, J Cleland, JG Kelly, SM Lyons… - Heart, 1975 - heart.bmj.com
Plasma myocardial, and skeletal muscle digoxin concentrations were measured in 32
patients undergoing cardiopulmonary bypass who were on long-term treatment with digoxin …