Functional characterization of 67 endocytic accessory proteins using multiparametric quantitative analysis of CCP dynamics

M Bhave, RE Mino, X Wang, J Lee… - Proceedings of the …, 2020 - National Acad Sciences
Clathrin-mediated endocytosis (CME) begins with the nucleation of clathrin assembly on the
plasma membrane, followed by stabilization and growth/maturation of clathrin-coated pits …

Imaging endocytic clathrin structures in living cells

T Kirchhausen - Trends in cell biology, 2009 - cell.com
Our understanding of the clathrin-dependent endocytic pathway owes much to new
visualization techniques. Budding coated pits and clathrin-coated structures are transient …

Temporal ordering in endocytic clathrin-coated vesicle formation via AP2 phosphorylation

AG Wrobel, Z Kadlecova, J Kamenicky, JC Yang… - Developmental Cell, 2019 - cell.com
Clathrin-mediated endocytosis (CME) is key to maintaining the transmembrane protein
composition of cells' limiting membranes. During mammalian CME, a reversible …

Imaging vesicle formation dynamics supports the flexible model of clathrin-mediated endocytosis

TJ Nawara, YD Williams, TC Rao, Y Hu, E Sztul… - Nature …, 2022 - nature.com
Clathrin polymerization and changes in plasma membrane architecture are necessary steps
in forming vesicles to internalize cargo during clathrin-mediated endocytosis (CME) …

Clathrin-mediated endocytosis: membrane factors pull the trigger

K Takei, V Haucke - Trends in cell biology, 2001 - cell.com
Clathrin-mediated endocytosis is a vesicular transport event involved in the internalization
and recycling of receptors participating in signal transduction events and nutrient import as …

Induced nanoscale membrane curvature bypasses the essential endocytic function of clathrin

RC Cail, CR Shirazinejad, DG Drubin - Journal of Cell Biology, 2022 - rupress.org
During clathrin-mediated endocytosis (CME), flat plasma membrane is remodeled to
produce nanometer-scale vesicles. The mechanisms underlying this remodeling are not …

Clathrin coats partially preassemble and subsequently bend during endocytosis

M Mund, A Tschanz, YL Wu, F Frey, JL Mehl… - Journal of Cell …, 2023 - rupress.org
Eukaryotic cells use clathrin-mediated endocytosis to take up a large range of extracellular
cargo. During endocytosis, a clathrin coat forms on the plasma membrane, but it remains …

An alternative mechanism of clathrin-coated pit closure revealed by ion conductance microscopy

AI Shevchuk, P Novak, M Taylor, IA Diakonov… - Journal of Cell …, 2012 - rupress.org
Current knowledge of the structural changes taking place during clathrin-mediated
endocytosis is largely based on electron microscopy images of fixed preparations and x-ray …

Selective regulation of clathrin-mediated epidermal growth factor receptor signaling and endocytosis by phospholipase C and calcium

RC Delos Santos, S Bautista, S Lucarelli… - Molecular Biology of …, 2017 - Am Soc Cell Biol
Clathrin-mediated endocytosis is a major regulator of cell-surface protein internalization.
Clathrin and other proteins assemble into small invaginating structures at the plasma …

Complete reconstitution of clathrin basket formation with recombinant protein fragments: Adaptor control of clathrin self‐assembly

B Greene, SH Liu, A Wilde, FM Brodsky - traffic, 2000 - Wiley Online Library
Clathrin polymerization into a polyhedral basket, surrounding budding membrane vesicles,
mediates protein sorting during endocytosis and organelle biogenesis. Adaptor proteins …