Attention-deficit/hyperactivity disorder polygenic risk scores predict attention problems in a population-based sample of children
MM Groen-Blokhuis, CM Middeldorp, KJ Kan… - Journal of the American …, 2014 - Elsevier
Objective Clinically, attention-deficit/hyperactivity disorder (ADHD) is characterized by
hyperactivity, impulsivity, and inattention and is among the most common childhood …
hyperactivity, impulsivity, and inattention and is among the most common childhood …
[HTML][HTML] Translating discoveries in attention-deficit/hyperactivity disorder genomics to an outpatient child and adolescent psychiatric cohort
Objective Genomic discoveries should be investigated in generalizable child psychiatric
samples in order to justify and inform studies that will evaluate their use for specific clinical …
samples in order to justify and inform studies that will evaluate their use for specific clinical …
[HTML][HTML] Genetic risk for attention-deficit/hyperactivity disorder contributes to neurodevelopmental traits in the general population
J Martin, ML Hamshere, E Stergiakouli… - Biological …, 2014 - Elsevier
Background Attention-deficit/hyperactivity disorder (ADHD) can be viewed as the extreme
end of traits in the general population. Epidemiological and twin studies suggest that ADHD …
end of traits in the general population. Epidemiological and twin studies suggest that ADHD …
[HTML][HTML] Shared genetic influences between attention-deficit/hyperactivity disorder (ADHD) traits in children and clinical ADHD
E Stergiakouli, J Martin, ML Hamshere… - Journal of the American …, 2015 - Elsevier
Objective Twin studies and genome-wide complex trait analysis (GCTA) are not in
agreement regarding heritability estimates for behavioral traits in children from the general …
agreement regarding heritability estimates for behavioral traits in children from the general …
[HTML][HTML] Systematic review: how the attention-deficit/hyperactivity disorder polygenic risk score adds to our understanding of ADHD and associated traits
A Ronald, N de Bode, TJC Polderman - … of the American Academy of Child …, 2021 - Elsevier
Objective To investigate, by systematically reviewing the literature, whether the attention-
deficit/hyperactivity disorder (ADHD) polygenic risk score (PRS) associates with ADHD and …
deficit/hyperactivity disorder (ADHD) polygenic risk score (PRS) associates with ADHD and …
Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder
OBJECTIVE: Although twin and family studies have shown attention-deficit/hyperactivity
disorder (ADHD) to be highly heritable, genetic variants influencing the trait at a genome …
disorder (ADHD) to be highly heritable, genetic variants influencing the trait at a genome …
A genome-wide association meta-analysis of attention-deficit/hyperactivity disorder symptoms in population-based pediatric cohorts
CM Middeldorp, AR Hammerschlag, KG Ouwens… - Journal of the American …, 2016 - Elsevier
Objective The aims of this study were to elucidate the influence of common genetic variants
on childhood attention-deficit/hyperactivity disorder (ADHD) symptoms, to identify genetic …
on childhood attention-deficit/hyperactivity disorder (ADHD) symptoms, to identify genetic …
Novel loci associated with attention-deficit/hyperactivity disorder are revealed by leveraging polygenic overlap with educational attainment
AA Shadrin, OB Smeland, T Zayats, AJ Schork… - Journal of the American …, 2018 - Elsevier
Objective Attention-deficit/hyperactivity disorder (ADHD) is a common and highly heritable
psychiatric condition. By exploiting the reported relationship between ADHD and …
psychiatric condition. By exploiting the reported relationship between ADHD and …
Candidate genetic pathways for attention-deficit/hyperactivity disorder (ADHD) show association to hyperactive/impulsive symptoms in children with ADHD
Objective Because multiple genes with small effect sizes are assumed to play a role in
attention-deficit/hyperactivity disorder (ADHD) etiology, considering multiple variants within …
attention-deficit/hyperactivity disorder (ADHD) etiology, considering multiple variants within …
The contribution of common genetic risk variants for ADHD to a general factor of childhood psychopathology
Common genetic risk variants have been implicated in the etiology of clinical attention-
deficit/hyperactivity disorder (ADHD) diagnoses and symptoms in the general population …
deficit/hyperactivity disorder (ADHD) diagnoses and symptoms in the general population …