Attention-deficit/hyperactivity disorder polygenic risk scores predict attention problems in a population-based sample of children

MM Groen-Blokhuis, CM Middeldorp, KJ Kan… - Journal of the American …, 2014 - Elsevier
Objective Clinically, attention-deficit/hyperactivity disorder (ADHD) is characterized by
hyperactivity, impulsivity, and inattention and is among the most common childhood …

[HTML][HTML] Translating discoveries in attention-deficit/hyperactivity disorder genomics to an outpatient child and adolescent psychiatric cohort

PJ Vuijk, J Martin, EB Braaten, G Genovese… - Journal of the American …, 2020 - Elsevier
Objective Genomic discoveries should be investigated in generalizable child psychiatric
samples in order to justify and inform studies that will evaluate their use for specific clinical …

[HTML][HTML] Genetic risk for attention-deficit/hyperactivity disorder contributes to neurodevelopmental traits in the general population

J Martin, ML Hamshere, E Stergiakouli… - Biological …, 2014 - Elsevier
Background Attention-deficit/hyperactivity disorder (ADHD) can be viewed as the extreme
end of traits in the general population. Epidemiological and twin studies suggest that ADHD …

[HTML][HTML] Shared genetic influences between attention-deficit/hyperactivity disorder (ADHD) traits in children and clinical ADHD

E Stergiakouli, J Martin, ML Hamshere… - Journal of the American …, 2015 - Elsevier
Objective Twin studies and genome-wide complex trait analysis (GCTA) are not in
agreement regarding heritability estimates for behavioral traits in children from the general …

[HTML][HTML] Systematic review: how the attention-deficit/hyperactivity disorder polygenic risk score adds to our understanding of ADHD and associated traits

A Ronald, N de Bode, TJC Polderman - … of the American Academy of Child …, 2021 - Elsevier
Objective To investigate, by systematically reviewing the literature, whether the attention-
deficit/hyperactivity disorder (ADHD) polygenic risk score (PRS) associates with ADHD and …

Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder

BM Neale, SE Medland, S Ripke, P Asherson… - Journal of the American …, 2010 - Elsevier
OBJECTIVE: Although twin and family studies have shown attention-deficit/hyperactivity
disorder (ADHD) to be highly heritable, genetic variants influencing the trait at a genome …

A genome-wide association meta-analysis of attention-deficit/hyperactivity disorder symptoms in population-based pediatric cohorts

CM Middeldorp, AR Hammerschlag, KG Ouwens… - Journal of the American …, 2016 - Elsevier
Objective The aims of this study were to elucidate the influence of common genetic variants
on childhood attention-deficit/hyperactivity disorder (ADHD) symptoms, to identify genetic …

Novel loci associated with attention-deficit/hyperactivity disorder are revealed by leveraging polygenic overlap with educational attainment

AA Shadrin, OB Smeland, T Zayats, AJ Schork… - Journal of the American …, 2018 - Elsevier
Objective Attention-deficit/hyperactivity disorder (ADHD) is a common and highly heritable
psychiatric condition. By exploiting the reported relationship between ADHD and …

Candidate genetic pathways for attention-deficit/hyperactivity disorder (ADHD) show association to hyperactive/impulsive symptoms in children with ADHD

J Bralten, B Franke, I Waldman, N Rommelse… - Journal of the American …, 2013 - Elsevier
Objective Because multiple genes with small effect sizes are assumed to play a role in
attention-deficit/hyperactivity disorder (ADHD) etiology, considering multiple variants within …

The contribution of common genetic risk variants for ADHD to a general factor of childhood psychopathology

I Brikell, H Larsson, Y Lu, E Pettersson, Q Chen… - Molecular …, 2020 - nature.com
Common genetic risk variants have been implicated in the etiology of clinical attention-
deficit/hyperactivity disorder (ADHD) diagnoses and symptoms in the general population …