We describe a new, spontaneously occurring BALB/c‐derived murine T‐cell leukemia. The
leukemic cells, designated LB, grow rapidly and progressively in the syngeneic host with no …

In order to study the possible role of the T-lymphocyte growth factor, Interleukin 2 (IL-2),
and/or of the IL-2 receptor in the autonomous growth of leukaemic cells, 15 mouse …

A continuous cell line was established from the blood of a patient (HH) with an aggressive
cutaneous T‐cell leukemia/lymphoma who lacked antibodies to human T lymphotrophic …

In mature T lymphocytes (T cells) the regulated expression of the genes for interleukin‐2 (IL‐
2) and its receptor (IL‐2R) constitutes an essential part in controlling the cell growth …

Background Previous studies have suggested that some of the limitations associated with
the administration of high-dose exogenous interleukin 2 (IL2) may be overcome, at least …

To elucidate the relationship between malignant transformation and cytokine receptor
expression, the interleukin-3 receptor (IL-3R) complex was examined in an IL-3-dependent …

Adult T-cell leukemia (ATL) cells have been shown to express the receptor for IL-2 by
studies using anti-CD25 monoclonal antibody, but these cells usually show no or only a …

We studied the expression of the receptor of interleukin (IL)‐4, one of the T cell growth
factors, on fresh peripheral blood leukemic cells from adult T‐cell leukemia (ATL) patients …

The induction of a T-cell immune response to a foreign antigen requires the activation of T-
lymphocytes that is initiated by the interaction of the T-cell antigen receptor with antigen …

Abstract Interleukin-2 (IL-2) for a long time has been considered as a T-cell specific growth
factor which acts through distinct surface receptors present on activated, but not on resting, T …