Annexin 1 binds to U937 monocytic cells and inhibits their adhesion to microvascular endothelium: involvement of the α4β1 integrin

E Solito, IA Romero, S Marullo… - The Journal of …, 2000 - journals.aai.org
Abstract Annexin 1 (ANX1), a calcium-binding protein, participates in the regulation of early
inflammatory responses. Whereas some of its effects depend on intracellular interactions, a …

Annexin 1 modulates monocyte-endothelial cell interaction in vitro and cell migration in vivo in the human SCID mouse transplantation model

M Perretti, F Ingegnoli, SK Wheller… - The Journal of …, 2002 - journals.aai.org
The effect of the glucocorticoid inducible protein annexin 1 (ANXA1) on the process of
monocytic cell migration was studied using transfected U937 cells expressing variable …

Annexin 1 and neutrophil apoptosis

M Perretti, E Solito - 2004 - portlandpress.com
ANXA1 (annexin 1), a member of the 'annexin'family of calcium-and phospholipid-binding
proteins, was originally identified as an endogenous mediator of the anti-inflammatory …

Neutrophil interaction with inflamed postcapillary venule endothelium alters annexin 1 expression

SM Oliani, MJ Paul-Clark, HC Christian… - The American journal of …, 2001 - Elsevier
Annexin 1 (ANX-A1) exerts antimigratory actions in several models of acute and chronic
inflammation. This is related to its ability to mimic the effect of endogenous ANX-A1 that is …

More than just innate affairs–on the role of annexins in adaptive immunity

H Weyd - Biological Chemistry, 2016 - degruyter.com
In more than 30 years of research annexins have been demonstrated to regulate immune
responses. The prototype member of this family, annexin (Anx) A1, has been widely …

Evidence for specific annexin I-binding proteins on human monocytes

NJ GOULDING, L PAN, K WARDWELL… - Biochemical …, 1996 - portlandpress.com
Recombinant human annexin I and a monoclonal antibody specific for this protein (mAb 1B)
were used to investigate surface binding of this member of the annexin family of proteins to …

Annexin A6 regulates interleukin‐2‐mediated T‐cell proliferation

R Cornely, AH Pollock, C Rentero… - Immunology and cell …, 2016 - Wiley Online Library
Annexin A6 (AnxA6) has been implicated in cell signalling by contributing to the
organisation of the plasma membrane. Here we examined whether AnxA6 regulates …

A potential role for annexin 1 as a physiologic mediator of glucocorticoid-induced L-selectin shedding from myeloid cells

HJ Strausbaugh, SD Rosen - The Journal of Immunology, 2001 - journals.aai.org
Glucocorticoids can dampen inflammatory responses by inhibiting neutrophil recruitment to
tissue sites. The detailed mechanism by which glucocorticoids exert this affect on …

Annexin A5 binds to lipopolysaccharide and reduces its endotoxin activity

JH Rand, XX Wu, EY Lin, A Griffel, P Gialanella… - MBio, 2012 - Am Soc Microbiol
ABSTRACT Annexin A5 (AnxA5) has a high affinity for phosphatidylserine. The protein is
widely used to detect apoptotic cells because phosphatidylserine, a phospholipid that is …

IL-6 stimulates annexin 1 expression and translocation and suggests a new biological role as class II acute phase protein

E Solito, C de Coupade, L Parente, RJ Flower… - Cytokine, 1998 - Elsevier
Annexin 1 (Ax 1), a protein whose synthesis and secretion are induced during the
inflammatory response, has been proposed as a mediator of the anti-inflammatory action of …