Impact of dabigatran on a large panel of routine or specific coagulation assays
J Douxfils, F Mullier, S Robert… - Thrombosis and …, 2012 - thieme-connect.com
Due to low bioavailability and high inter-individual variability, monitoring of dabigatran may
be required in specific situations to prevent the risk of bleedings or thrombosis. The aim of …
be required in specific situations to prevent the risk of bleedings or thrombosis. The aim of …
Performance of coagulation tests in patients on therapeutic doses of dabigatran: a cross‐sectional pharmacodynamic study based on peak and trough plasma levels
EM Hawes, AM Deal, D Funk‐Adcock… - … of Thrombosis and …, 2013 - Wiley Online Library
Background Knowledge of anticoagulation status during dabigatran therapy may be
desirable in certain clinical situations. Objective To determine the coagulation tests that are …
desirable in certain clinical situations. Objective To determine the coagulation tests that are …
Dabigatran effects on the international normalized ratio, activated partial thromboplastin time, thrombin time, and fibrinogen: a multicenter, in vitro study
WE Dager, RC Gosselin, S Kitchen… - Annals of …, 2012 - journals.sagepub.com
Background: Patients receiving the direct thrombin inhibitor dabigatran may have selected
anticoagulation assays performed as part of routine care. The effect of dabigatran on the …
anticoagulation assays performed as part of routine care. The effect of dabigatran on the …
Evaluation of coagulation assays versus LC-MS/MS for determinations of dabigatran concentrations in plasma
JP Antovic, M Skeppholm, J Eintrei, EE Boija… - European journal of …, 2013 - Springer
Background Dabigatran is an oral direct thrombin inhibitor for which routine laboratory
monitoring is currently not recommended. However, there are situations in which …
monitoring is currently not recommended. However, there are situations in which …
Comparison of calibrated dilute thrombin time and aPTT tests with LC-MS/MS for the therapeutic monitoring of patients treated with dabigatran etexilate
Ways to monitor dabigatran etexilate (DE) therapy would be useful in certain situations.
Functional assays such as aPTT or Hemoclot® Thrombin Inhibitor (HTI) have been …
Functional assays such as aPTT or Hemoclot® Thrombin Inhibitor (HTI) have been …
Effects of the oral, direct thrombin inhibitor dabigatran on five common coagulation assays
TL Lindahl, F Baghaei, IF Blixter… - Thrombosis and …, 2011 - thieme-connect.com
Dabigatran is an oral, reversible thrombin inhibitor that has shown promising results in large
clinical trials. Laboratory monitoring is not needed but the effects on common coagulation …
clinical trials. Laboratory monitoring is not needed but the effects on common coagulation …
The effect of dabigatran on the activated partial thromboplastin time and thrombin time as determined by the Hemoclot thrombin inhibitor assay in patient plasma …
G Hapgood, J Butler, E Malan… - Thrombosis and …, 2013 - thieme-connect.com
Dabigatran is an oral direct thrombin inhibitor that does not require routine laboratory
monitoring. However, an assessment of its anticoagulant effect in certain clinical settings is …
monitoring. However, an assessment of its anticoagulant effect in certain clinical settings is …
Using the HEMOCLOT direct thrombin inhibitor assay to determine plasma concentrations of dabigatran
J Stangier, M Feuring - Blood coagulation & fibrinolysis, 2012 - journals.lww.com
The objective of the present study was to assess the suitability of an accurate, sensitive,
standardized, chronometric blood coagulation test to determine the anticoagulation activity …
standardized, chronometric blood coagulation test to determine the anticoagulation activity …
Dabigatran etexilate–a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity
J Van Ryn, J Stangier, S Haertter… - Thrombosis and …, 2010 - thieme-connect.com
Dabigatran etexilate is an oral, reversible direct thrombin inhibitor that is approved in the EU
and several other countries for the prevention of venous thromboembolism after elective hip …
and several other countries for the prevention of venous thromboembolism after elective hip …
The acute management of haemorrhage, surgery and overdose in patients receiving dabigatran
R Alikhan, R Rayment, D Keeling, T Baglin… - Emergency Medicine …, 2014 - emj.bmj.com
Dabigatran is an oral direct thrombin inhibitor (DTI) licensed for stroke prevention in atrial
fibrillation and likely to be soon approved in Europe for treatment of venous thrombosis …
fibrillation and likely to be soon approved in Europe for treatment of venous thrombosis …
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