Porphyromonas gingivalis Gingipains and Adhesion to Epithelial Cells

T Chen, K Nakayama, L Belliveau… - Infection and …, 2001 - Am Soc Microbiol
Porphyromonas gingivalis is one of the principal organisms associated with adult
periodontitis. Bacterial surface proteins such as fimbriae and gingipain hemagglutinin …

Gingipain adhesin domains mediate Porphyromonas gingivalis adherence to epithelial cells

T Chen, MJ Duncan - Microbial pathogenesis, 2004 - Elsevier
Porphyromonas gingivalis, a Gram-negative oral anaerobe, interacts with epithelium lining
the gingival sulcus. Continuing our studies on the role of gingipain cysteine proteinases in P …

Hydrolysis of Epithelial Junctional Proteins by Porphyromonas gingivalis Gingipains

J Katz, QB Yang, P Zhang, J Potempa… - Infection and …, 2002 - Am Soc Microbiol
Porphyromonas gingivalis has been implicated as an etiologic agent of adult periodontitis.
We have previously shown that P. gingivalis can degrade the epithelial cell-cell junction …

Role of fimbriae in Porphyromonas gingivalis invasion of gingival epithelial cells

A Weinberg, CM Belton, Y Park… - Infection and …, 1997 - Am Soc Microbiol
Porphyromonas gingivalis is a periodontal pathogen capable of invading primary cultures of
normal human gingival epithelial cells (NHGEC). Involvement of P. gingivalis fimbriae in the …

Effect of Inactivation of the Arg- and/or Lys-Gingipain Gene on Selected Virulence and Physiological Properties of Porphyromonas gingivalis

D Grenier, S Roy, F Chandad, P Plamondon… - Infection and …, 2003 - Am Soc Microbiol
Proteolytic enzymes produced by Porphyromonas gingivalis are thought to play critical roles
in the pathogenesis of periodontitis. The aim of this study was to investigate the effect of …

Porphyromonas gingivalis Fimbriae Bind to Cytokeratin of Epithelial Cells

HT Sojar, A Sharma, RJ Genco - Infection and immunity, 2002 - Am Soc Microbiol
The adherence of Porphyromonas gingivalis to host cells is likely a prerequisite step in the
pathogenesis of P. gingivalis-induced periodontal disease. P. gingivalis binds to and …

Clathrin‐dependent entry of a gingipain adhesin peptide and Porphyromonas gingivalis into host cells

H Boisvert, MJ Duncan - Cellular microbiology, 2008 - Wiley Online Library
Porphyromonas gingivalis, a Gram‐negative oral anaerobe, is associated with periodontitis,
a disease that in some form affects up to 80% of the adult population in the USA. The …

Role of Porphyromonas gingivalis protease activity in colonization of oral surfaces

M Tokuda, M Duncan, MI Cho… - Infection and …, 1996 - Am Soc Microbiol
Cysteine proteases, including Arg-gingipain of Porphyromonas gingivalis, have been
implicated as important virulence factors in periodontal diseases. These enzymes are also …

Invasion of Epithelial Cells and Proteolysis of Cellular Focal Adhesion Components by Distinct Types of Porphyromonas gingivalis Fimbriae

I Nakagawa, H Inaba, T Yamamura, T Kato… - Infection and …, 2006 - Am Soc Microbiol
Porphyromonas gingivalis fimbriae are classified into six types (types I to V and Ib) based on
the fimA genes encoding FimA (a subunit of fimbriae), and they play a critical role in …

Fimbriae and the hemagglutinating adhesin HA-Ag2 mediate adhesion of Porphyromonas gingivalis to epithelial cells

L Du, P Pellen-Mussi, F Chandad, C Mouton… - Infection and …, 1997 - Am Soc Microbiol
The mechanisms by which Porphyromonas gingivalis, a gram-negative anaerobic
bacterium, is pathogenic for the periodontium remain largely hypothetical. Invasion of host …