Background We previously showed that nano-hydroxyapatite/carboxymethyl chitosan (n-
Ha/CMCS) displayed excellent mechanical properties, good degradation rates and …

In this study, hierarchical collagen scaffolds consisting of micro-strut collagen and
electrospun poly (ε-caprolactone)(PCL)/β-tricalcium phosphate (TCP) nanofibres were …

Biomineralization is a process in which natural organisms regulate the crystal growth of
inorganic minerals, resulting in hierarchical structured biominerals with excellent properties …

Objectives Large bone defects are a common, debilitating clinical condition that have
substantial global health and economic burden. Bone tissue engineering technology has …

Porous materials and scaffolds have wide applications in biomedical and biological fields.
They can provide biological and physical cues to promote cell adhesion, proliferation …

Human umbilical cord-derived mesenchymal stem cells (UC-MSCs) have attracted great
interest in clinical application because of their regenerative potential and their lack of ethical …

This work explores in depth the simultaneous self‐assembly and mineralization of type I
collagen by a base‐acid neutralization technique to prepare biomimetic collagen‐apatite …

INTRODUCTION: A potent mesenchymal stem cell (MSC) population was recently isolated
from the Wharton's jelly of human umbilical cord (UC). The aim of the current experiments …

This study investigated the potential of amniotic fluid stem cells (AFSCs) to synthesize
mineralized extracellular matrix (ECM) within different porous scaffolds of collagen, poly-d, l …

Alkaline phosphatase (ALP) and phosphoprotein participation in collagen mineralization is
one of the most important physiological processes of bone formation. Simulating the natural …