Protection of the ischaemic heart: investigations into the phenomenon of ischaemic preconditioning

A Lochner, E Marais, S Genade… - … journal of Africa, 2009 - journals.co.za
Exposure of the heart to one or more short episodes of ischaemia/reperfusion protects the
heart against a subsequent prolonged period of ischaemia, as evidenced by a reduction in …

Anti-arrhythmic protection by ischaemic preconditioning in isolated rat hearts is not due to depletion of endogenous catecholamines

CS Lawson, DJ Hearse - Cardiovascular research, 1996 - academic.oup.com
Objectives: The present study addresses whether the mechanism of anti-arrhythmic
protection by ischaemic preconditioning involves depletion of myocardial catecholamines …

[引用][C] Does ischaemic preconditioning occur in the human heart?

CS Lawson - Cardiovascular research, 1994 - academic.oup.com
he description of ischaemic preconditioning by Muny et dl in 1986 has substantially altered
the way in T which we think about the pathophysiological processes involved in acute …

Ischaemic postconditioning: from bench to bedside...

D Van Vuuren, A Lochner - Cardiovascular Journal of Africa, 2008 - journals.co.za
The increase in the incidence of ischaemic heart disease and acute myocardial infarction
(AMI) in both high-and low-income countries necessitates the development of myocardial …

An in vivo model of ischaemia–reperfusion injury and ischaemic preconditioning in the mouse heart

SG Fisher, MS Marber - Journal of pharmacological and toxicological …, 2002 - Elsevier
Introduction: Our aim was to develop a robust protocol for inducing ischaemia–reperfusion
injury and preconditioning in the in vivo mouse heart. Methods: Animals were prepared by …

Ischaemic preconditioning is protein kinase C dependent but not through stimulation of α adrenergic or adenosine receptors in the isolated rat heart

E Bugge, K Ytrehus - Cardiovascular research, 1995 - academic.oup.com
Abstract Objective: The aim was (1) to clarify whether α adrenoceptor and adenosine
receptor stimulation is involved in the anti-infarct effect of ischaemic preconditioning in the …

Combined pharmacological preconditioning with a G‐protein‐coupled receptor agonist, a mitochondrial KATP channel opener and a nitric oxide donor mimics …

H Otani, T Okada, H Fujiwara… - Clinical and …, 2003 - Wiley Online Library
Although pharmacological preconditioning (PPC) has emerged as an alternative to
ischaemic preconditioning (IPC) in cardioprotection, the efficacy of PPC compared with IPC …

[PDF][PDF] Ischaemic preconditioning: from molecular characterisation to clinical application-part I

NP Riksen, P Smits, GA Rongen - Neth J Med, 2004 - njmonline.nl
Ischaemic preconditioning is defined as an increased tolerance to ischaemia and
reperfusion induced by a previous sublethal period of ischaemia. Since this is the most …

Pronounced antiarrhythmic effects preconditioning in anaesthetized dogs: is adenosine involved?

A Vegh, JG Papp, JR Parratt - Journal of molecular and cellular cardiology, 1995 - Elsevier
A. Vegh, J. Gy Papp and JR Parratt. Pronounced Antiarrhythmic Effects of Preconditioning in
Anaesthetised Dogs: Is Adenosine Involved? Journal of Molecular and Cellular Cardiology …

Protection of the myocardium by ischaemic preconditioning: mechanisms and therapeutic implications

CGM Millar, GF Baxter, C Thiemermann - Pharmacology & therapeutics, 1996 - Elsevier
Preconditioning of the heart with brief periods of ischaemia protects the myocardium for up
to 90 min against a more sustained ischaemic injury. A “second window of protection” occurs …