Obesity is a risk factor for colorectal cancer, and hyperinsulinemia, a common condition in
obese patients, may underlie this relationship. Insulin, in addition to its metabolic effects, has …

Purpose Many studies suggest increased body mass index (BMI) is associated with worse
breast cancer outcomes, but few account for variability in screening, access to treatment …

Obesity, metabolic syndrome and type 2 diabetes are associated with cancer‐related
mortality. We assessed whether hyperinsulinemia is a risk factor for cancer death in …

Background: Obesity and the metabolic syndrome (MetS) have both been linked to
increased risk of postmenopausal breast cancer; however, their relative contributions are …

Studies investigating the potential link between adult pre-menopausal obesity [as measured
by body mass index (BMI)] and triple-negative breast cancer have been inconsistent. Recent …

Background Epidemiological evidence supports a positive association between circulating
insulin-like growth factor-1 (IGF-1) concentrations and breast cancer risk, but both the …

Importance Obesity is associated with an increased risk of breast cancer, including the
estrogen receptor (ER)–positive subtype in postmenopausal women. Whether excess …

Objective: To examine the possible relationships of breast cancer risk to prediagnostic
plasma levels of insulin; insulin-like growth factor-I (IGF-I); and IGF-binding proteins-1,-2 …

The evidence for anthropometric factors influencing breast cancer risk is accumulating, but
uncertainties remain concerning the role of fat distribution and potential effect modifiers. We …

High circulating glucose, insulin resistance and obesity appear to be associated with
increased risk of breast cancer (BC). We sought further insight into the relation of these …