The pathogenesis of coronary artery disease (CAD) is closely associated with inflammation,
in which human leukocyte antigens (HLA), especially HLA-DR molecules, play important …

Accumulated evidence indicates that polymorphisms in human leukocyte antigens (HLA) are
associated with susceptibility to coronary artery disease (CAD). However, whether HLA …

Abstract CD4+ CD28 null T cells are present in increased numbers in the peripheral blood of
patients with acute coronary syndrome. However, the triggers of expansion of these cells are …

Background: Human leukocyte antigen (HLA) complex is a gene family involved in antigen
presentation associated with protection or susceptibility to inflammatory, infectious and …

Coronary atherosclerotic disease is one of the most endangering health disorder worldwide.
This study was designed to investigate the correlation between HLA-DRb1 alleles and …

Objectives HLA-DRB1 is associated with an increased risk of cardiovascular disease in
patients with rheumatoid arthritis (RA). This study aimed to determine the effect of HLA …

Aiming to study the role of human major histocompatibility complex (MHC) region on
coronary artery disease (CAD), we enrolled two separate patient materials and controls …

Björkbacka H, Lavant EH, Fredrikson GN, Melander O, Berglund G, Carlson JA, Nilsson J
(Lund University, Malmö University Hospital, Malmö; and Lund University, Lund University …

Background Rheumatic fever (RF) and its sequel rheumatic heart disease (RHD) is an
autoimmune disease caused by an abnormal host immune response to group A …

This case–control study was carried out to investigate the possible relationship between the
gene frequencies of HLA-DRB1,-DQA1 and-DQB1 alleles/haplotypes and rheumatic heart …