The advent of neuroimaging has increased our understanding of brain function. While most
brain-wide functional imaging modalities exploit neurovascular coupling to map brain …

Non-invasive imaging deep into organs at microscopic scales remains an open quest in
biomedical imaging. Although optical microscopy is still limited to surface imaging owing to …

Abstract Changes in cerebral blood flow are associated with stroke, aneurysms, vascular
cognitive impairment, neurodegenerative diseases and other pathologies. Brain …

Background Non-invasive high-resolution imaging of the cerebral vascular anatomy and
function is key for the study of intracranial aneurysms, stenosis, arteriovenous …

Medical ultrasound is a widely used diagnostic imaging technique for tissues and blood
vessels. However, its spatial resolution is limited to a sub-millimeter scale. Ultrasound …

Objective: Ultrasound Localization Microscopy (ULM) provides images of the
microcirculation in-depth in living tissue. However, its implementation in two-dimension is …

Aging-related cognitive decline is an emerging health crisis; however, no established
unifying mechanism has been identified for the cognitive impairments seen in an aging …

Rationale: Structure and function of the microvasculature provides critical information about
disease state, can be used to identify local regions of pathology, and has been shown to be …

We present functional ultrasound (fUS), a method for imaging transient changes in blood
volume in the whole brain at better spatiotemporal resolution than with other functional brain …

Functional ultrasound imaging (fUS) is an emerging technique that detects changes of
cerebral blood volume triggered by brain activation. Here, we investigate the extent to which …