Muscle contraction consists of a cyclical interaction between myosin and actin driven by the
concomitant hydrolysis of adenosine triphosphate (ATP). A model for the rigor complex of F …

Muscle contraction involves the cyclic interaction of the myosin cross-bridges with the actin
filament, which is coupled to steps in the hydrolysis of ATP. While bound to actin each cross …

Muscle contraction occurs when the actin and myosin filaments in muscle are driven past
each other by a cyclic interaction of adenosine triphosphate (ATP) and actin with cross …

The dynamics and polarity of actin filaments are controlled by a conformational change
coupled to the hydrolysis of adenosine 5′-triphosphate (ATP) by a mechanism that remains …

F-actin is the major component of muscle thin filaments and, more generally, of the
microfilaments of the dynamic, multifunctional cytoskeletal systems of nonmuscle eukaryotic …

Directed movement is a characteristic of many living organisms and occurs as a result of the
transformation of chemical energy into mechanical energy. Myosin is one of three families of …

In the energy transduction of muscle contraction, it is important to know the nature and extent
of conformational changes of the head portion of the myosin molecules. In the presence of …

During the last several years, the major challenge in the field of muscle contraction has been
to develop a detailed theory explaining how muscle develops force and produces work …

Actomyosin, a complex of actin filaments and myosin motor proteins, is responsible for force
generation during muscle contraction. To resolve the individual mechanical events of force …

Tropomyosin is a regulatory protein associated with F-actin in many actomyosin contractile
systems. If in vitro conditions are such that tropomyosin binds only slightly to F-actin, then the …