Assessment of perceived cost to the patient and other barriers to clinical trial participation

DJ Weckstein, CA Thomas, IF Emery… - Journal of Oncology …, 2011 - ascopubs.org
Purpose: Less than 5% of patients with cancer participate in trials. Few studies have
specifically addressed the role of cost to the patient as an influence on trial participation. Our …

Barriers to clinical trial participation as perceived by oncologists and patients

NJ Meropol, JS Buzaglo, J Millard, N Damjanov… - Journal of the National …, 2007 - jnccn.org
Although clinical trial research is required for the development of improved treatment
strategies, very few cancer patients participate in these studies. The purpose of this study …

Access to clinical trials among oncology patients: results of a cross sectional survey

M Carey, AW Boyes, R Smits, J Bryant, A Waller, I Olver - BMC cancer, 2017 - Springer
Background Clinical trials are necessary for the advancement of cancer treatment and care,
however low rates of participation in such trials limit the generalisability of findings. The …

Systematic review and meta-analysis of the magnitude of structural, clinical, and physician and patient barriers to cancer clinical trial participation

JM Unger, R Vaidya, DL Hershman… - JNCI: Journal of the …, 2019 - academic.oup.com
Background Barriers to cancer clinical trial participation have been the subject of frequent
study, but the rate of trial participation has not changed substantially over time. Studies often …

[HTML][HTML] Role of clinical trial participation in cancer research: barriers, evidence, and strategies

JM Unger, E Cook, E Tai, A Bleyer - American Society of Clinical …, 2016 - ncbi.nlm.nih.gov
Fewer than 1 in 20 adult cancer patients enroll in cancer clinical trials. But although barriers
to trial participation have been the subject of frequent study, the rate of trial participation has …

Nationally representative estimates of the participation of cancer patients in clinical research studies according to the commission on cancer.

JM Unger, M Fleury - 2021 - ascopubs.org
74 Background: The successful conduct of cancer clinical trials hinges on the willingness of
patients to participate. The rate of adult clinical trial participation has been regarded as …

Barriers exist to patient participation in clinical trials

MJ Guarino, GA Masters, CJ Schneider… - Journal of Clinical …, 2005 - ascopubs.org
6015 Background: Multiple factors determine whether or not cancer pts enter a clinical trial.
To find some of these causes, a seven physician MedOnc/Hem practice with access to …

“When offered to participate”: a systematic review and meta-analysis of patient agreement to participate in cancer clinical trials

JM Unger, DL Hershman, C Till… - JNCI: Journal of the …, 2021 - academic.oup.com
Background Patient participation in clinical trials is vital for knowledge advancement and
outcomes improvement. Few adult cancer patients participate in trials. Although patient …

A systematic review highlights threats to validity in studies of barriers to cancer trial participation

D Fayter, C McDaid, A Eastwood - Journal of clinical epidemiology, 2007 - Elsevier
OBJECTIVE: To investigate the barriers, modifiers, and benefits involved in participating in
randomized controlled trials of cancer therapies as perceived by health care providers and …

Barriers to clinical trial enrollment: are state mandates the solution?

BE Hillner - Journal of the National Cancer Institute, 2004 - academic.oup.com
Everyone agrees that optimal medical care should be based upon a database of evidence
derived from patients participating in comparative randomized clinical trials. Unfortunately …