Sex hormones and novel corona virus infectious disease (COVID-19)

RA Al-Lami, RJ Urban, E Volpi, AMA Algburi… - Mayo Clinic …, 2020 - Elsevier
Given the rapid spread of the coronavirus disease 2019 (COVID-19) pandemic and its
overwhelming effect on health care systems and the global economy, innovative therapeutic …

Testosterone's Role in COVID-19

JM Auerbach, M Khera - The Journal of Sexual Medicine, 2021 - academic.oup.com
ABSTRACT COVID-19 consistently displays a higher mortality in males. This sex-specific
difference in outcomes is seen not only in the current COVID-19 pandemic, but also in prior …

Why do men have worse COVID-19-related outcomes? A systematic review and meta-analysis with sex adjusted for age

J Fabião, B Sassi, EF Pedrollo, F Gerchman… - Brazilian Journal of …, 2022 - SciELO Brasil
We aimed to study the mechanism behind worse coronavirus disease-19 (COVID-19)
outcomes in men and whether the differences between sexes regarding mortality as well as …

Immune mechanisms associated with sex-based differences in severe COVID-19 clinical outcomes

CG Arnold, A Libby, A Vest, A Hopkinson… - Biology of sex …, 2022 - Springer
Background Although biological males and females are equally likely to become infected
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), evidence has …

Are sex discordant outcomes in COVID-19 related to sex hormones?

JD Strope, CH Chau, WD Figg - Seminars in oncology, 2020 - Elsevier
COVID-19 has a clear sex disparity in clinical outcome. Globally, infection rates between
men and women are similar; however, men are more likely to have more severe disease …

Is COVID-19 gender-sensitive?

S Mukherjee, K Pahan - Journal of Neuroimmune Pharmacology, 2021 - Springer
While clinical characteristics exhibit that susceptibility to COVID-19 infection is equally likely
between males and females, clinical outcomes show that males experience both a higher …

The looming effects of estrogen in Covid-19: a rocky rollout

HM Al-Kuraishy, AI Al-Gareeb, H Faidah… - Frontiers in …, 2021 - frontiersin.org
In the face of the Covid-19 pandemic, an intensive number of studies have been performed
to understand in a deeper way the mechanisms behind better or worse clinical outcomes …

[HTML][HTML] Coronavirus: why men are more vulnerable to Covid-19 than women?

GM Bwire - SN comprehensive clinical medicine, 2020 - Springer
Amid of coronavirus disease 2019 (Covid-19) pandemic, much emphasis was initially
placed on the elderly or those who have preexisting health conditions such as obesity …

Worse progression of COVID‐19 in men: is testosterone a key factor?

VA Giagulli, E Guastamacchia, T Magrone, E Jirillo… - …, 2021 - Wiley Online Library
Background The novel severe acute respiratory syndrome coronavirus (SARS‐CoV‐2)
disease 2019 (COVID‐19) seems to have a worse clinical course among infected men …

Association of circulating sex hormones with inflammation and disease severity in patients with COVID-19

S Dhindsa, N Zhang, MJ McPhaul, Z Wu… - JAMA network …, 2021 - jamanetwork.com
Importance Male sex is a risk factor for developing severe COVID-19 illness. It is not known
whether sex hormones contribute to this predisposition. Objective To investigate the …