Inhibition of spinal nociceptive responses after intramuscular injection of capsaicin involves activation of noradrenergic and opioid systems
J Gjerstad, A Tjølsen, F Svendsen, K Hole - Brain research, 2000 - Elsevier
Extracellular recordings of wide dynamic range neurones in the dorsal horn driven by
electrical stimulation of the sciatic nerve were performed in intact urethane-anaesthetized …
electrical stimulation of the sciatic nerve were performed in intact urethane-anaesthetized …
Neurophysiological effects of capsaicin
LC Russell, KJ Burchiel - Brain Research Reviews, 1984 - Elsevier
Data obtained from neonatally treated rats are fairly consistent. However, there is
disagreement as to whether mechanical and thermal nociceptive thresholds are elevated or …
disagreement as to whether mechanical and thermal nociceptive thresholds are elevated or …
Pain, hyperalgesia and activity in nociceptive C units in humans after intradermal injection of capsaicin.
RH LaMotte, LE Lundberg… - The Journal of …, 1992 - Wiley Online Library
1. Capsaicin, the potent algesic substance in chilli peppers, was applied topically to, or
injected intradermally into or outside, the receptive fields of 14 C mechanoheat (polymodal) …
injected intradermally into or outside, the receptive fields of 14 C mechanoheat (polymodal) …
Resiniferatoxin, a potent capsaicin‐like stimulator of peripheral nociceptors in the neonatal rat tail in vitro
A Dray, J Bettaney, P Forster - British journal of pharmacology, 1990 - Wiley Online Library
1 A spinal ventral root response was measured following the activation of peripheral fibres
by noxious (heat at 48° C, capsaicin, bradykinin) and innocuous (brush) stimuli in a …
by noxious (heat at 48° C, capsaicin, bradykinin) and innocuous (brush) stimuli in a …
Perspectives of capsaicin-type agents in pain therapy and research
J Szolcsanyi - Contemporary issues in chronic pain management, 1991 - Springer
There is a" painfully" absent chapter in pharmacological textbooks, which could be entitled:"
Drugs acting on sensory neurons" or" Sensory neuronblocking analgesics." For over 100 …
Drugs acting on sensory neurons" or" Sensory neuronblocking analgesics." For over 100 …
Capsaicin depletes corticotropin-releasing factor-like immunoreactive neurons in the rat spinal cord and medulla oblongata
G Skofitsch, GS Hamill, DM Jacobowitz - Neuroendocrinology, 1984 - karger.com
Abstract Treatment of newborn rats with capsaicin was shown to cause a disappearance of
corticotropin-releasing factor immunoreactive nerve fibers in the dorsal horn of the spinal …
corticotropin-releasing factor immunoreactive nerve fibers in the dorsal horn of the spinal …
Sensory effects of capsaicin congeners I. Relationship between chemical structure and pain-producing potency of pungent agents.
J Szolcsányi, A Jancso-Gabor - Arzneimittel-Forschung, 1975 - europepmc.org
A quantitative method for measuring the efficiency of pungent agents of capsaicin-type by
the pain reaction elicited on the eye of rats is described. About 50 derivatives--most of them …
the pain reaction elicited on the eye of rats is described. About 50 derivatives--most of them …
Characterization of three different sensory fibers by use of neonatal capsaicin treatment, spinal antagonism and a novel electrical stimulation-induced paw flexion test
M Matsumoto, M Inoue, A Hald, A Yamaguchi… - Molecular …, 2006 - journals.sagepub.com
In the present study, we first report an in vivo characterization of flexor responses induced by
three distinct sine-wave stimuli in the electrical stimulation-induced paw flexion (EPF) test in …
three distinct sine-wave stimuli in the electrical stimulation-induced paw flexion (EPF) test in …
Spinal local anaesthetic actions on afferent evoked responses and wind-up of nociceptive neurones in the rat spinal cord: combination with morphine produces …
HM Fraser, V Chapman, AH Dickenson - Pain, 1992 - Elsevier
Lignocaine was tested either alone or in combination with a low dose of morphine by
intrathecal administration on the C-and A-beta evoked responses of nociceptive neurones in …
intrathecal administration on the C-and A-beta evoked responses of nociceptive neurones in …