Background Walking is a familiar daily activity that is generally limited by breathlessness,
whereas cycling is an uncommon physical effort typically limited by leg discomfort. The …

RATIONALE: Patients with mild chronic obstructive pulmonary disease (COPD) present
abnormal ventilatory mechanics during exercise and may require bronchodilator therapy …

Rationale: There is no consensus regarding which exercise test to use to evaluate the
functional impact of bronchodilators in patients with chronic obstructive pulmonary disease …

This study focused on repeatability data and minimal important difference (MID) estimates of
the endurance shuttle walking test (ESWT). 255 chronic obstructive pulmonary disease …

Background: Exercise tolerance is an important endpoint in chronic obstructive pulmonary
disease (COPD) clinical trials. Little is known about the comparative measurement …

Few studies have shown that the endurance shuttle walking test (ESWT) is responsive to
treatment in patients with chronic obstructive pulmonary disease (COPD). This exercise test …

BACKGROUND: Bronchial variability in COPD patients may be a phenotypic feature
associated with clinical characteristics and differential treatment response. We analyzed …

Background: The responsiveness of the endurance shuttle walk to functional changes
following bronchodilation has recently been reported. The current literature suggests that the …

Background Although the cycle ergometer is the traditional mode for exercise testing in
patients with respiratory disease, this preference over the treadmill does not consider …

Rationale: We examined the responsiveness of a 3-minute constant rate shuttle walking
protocol to detect improvements in exertional dyspnea following acute bronchodilation in …